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| | Pyridine-3-sulfonyl chloride hydrochloride Basic information |
| | Pyridine-3-sulfonyl chloride hydrochloride Chemical Properties |
| Melting point | 120-126 | | Fp | >110℃ | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | Appearance | white solid | | Water Solubility | Reacts with water. | | Sensitive | Moisture Sensitive |
| Hazard Codes | C | | Risk Statements | 14-29-34 | | Safety Statements | 8-22-26-30-45-36/37/39 | | RIDADR | UN 3265 8 / PGII | | Hazard Note | Corrosive/Keep Cold under -20C | | HazardClass | IRRITANT | | HazardClass | 8 | | HS Code | 29333990 |
| | Pyridine-3-sulfonyl chloride hydrochloride Usage And Synthesis |
| Chemical Properties | White solid | | Synthesis | General procedure for the synthesis of pyridine-3-sulfonyl chloride hydrochloride from 3-pyridinesulfonic acid: 3-pyridinesulfonic acid (3.00 g, 18.8 mmol) was mixed with phosphorus pentachloride (PCl5, 4.79 g, 23.0 mmol) in phosphorus oxychloride (POCl3, 6 mL). The reaction mixture was stirred and reacted at 120°C overnight (15 h). After completion of the reaction, it was cooled to room temperature, diluted with chloroform (CHCl3, 20 mL) and saturated with hydrogen chloride gas (HCl(g)). The precipitated white precipitate was collected by filtration, washed with chloroform and dried under reduced pressure to give the title compound pyridine-3-sulfonyl chloride hydrochloride (3.36 g, 83% yield) as a white powder. | | References | [1] Advanced Synthesis and Catalysis, 2004, vol. 346, # 8, p. 925 - 928
[2] Patent: WO2008/3703, 2008, A1. Location in patent: Page/Page column 82
[3] Patent: US2007/60623, 2007, A1. Location in patent: Page/Page column 24
[4] Patent: WO2006/36024, 2006, A1. Location in patent: Page/Page column 160
[5] Patent: EP2336107, 2015, B1. Location in patent: Paragraph 0306 |
| | Pyridine-3-sulfonyl chloride hydrochloride Preparation Products And Raw materials |
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