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| | SARS-CoV/SARS-CoV-2 Nucleocapsid Protein Rabbit Monoclonal Antibody (Clone 040) Basic information |
| | SARS-CoV/SARS-CoV-2 Nucleocapsid Protein Rabbit Monoclonal Antibody (Clone 040) Chemical Properties |
| | SARS-CoV/SARS-CoV-2 Nucleocapsid Protein Rabbit Monoclonal Antibody (Clone 040) Usage And Synthesis |
| Description | Severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 nucleocapsid proteins are encoded by the N gene in SARS-CoV and SARS-CoV-2 RNA.1,2 SARS-CoV and SARS-CoV-2 are members of the Betacoronavirus genus of viruses that have approximately 79% sequence identity and share 27 T cell epitopes in common.3,4,5 The SARS-CoV-2 nucleocapsid protein has greater than 90% similarity to the SARS-CoV nucleocapsid protein and contains two unique B cell epitopes and two T cell epitopes that are structurally stable, non-allergenic, and induce production of IFN-γ.5,2 SARS-CoV and SARS-CoV-2 nucleocapsid proteins package the viral RNA into a helical ribonucleoprotein complex (RNP), which is a template for viral replication, and are integral for viral self-assembly and involved in regulation of the host cell cycle.6,2 SARS-CoV and SARS-CoV-2 are the causative agents of SARS and COVID-19, respectively, both of which are primarily respiratory illnesses characterized by fever, cough, and shortness of breath that can lead to life-threatening complications.4,7,8 Cayman's SARS-CoV/SARS-CoV-2 Nucleocapsid Protein Rabbit Monoclonal Antibody (Clone 040) can be used for ELISA, immunocytochemistry (ICC), immunofluorescence (IF), and Western blot (WB) applications. This recombinant antibody recognizes wild-type and various mutant nucleocapsid proteins at 45.6 kDa from SARS-CoV, SARS-CoV-2, and several SARS-CoV-2 Alpha, Beta, Gamma, Delta, Eta, and Omicron subvariants.WARNING This product is not for human or veterinary use. |
| | SARS-CoV/SARS-CoV-2 Nucleocapsid Protein Rabbit Monoclonal Antibody (Clone 040) Preparation Products And Raw materials |
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