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| | 3-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE Basic information |
| Product Name: | 3-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE | | Synonyms: | 3-[4-(Diethylamino)-2-methylphenyl]-3-(1,2-dimethyl-1H-indol-3-yl)phthalide;3-[4-(Diethylamino)-2-methylphenyl]-3-(1,2-dimethyl-1H-indole-3-yl)-1(3H)-isobenzofuranone;3-(4-(diethylaMino)-2-Methylphenyl)-3-(1,2-diMethyl-1H-indol-3-yl)isobenzofuran-1(3H)-one;2-(2'-Methyl-4'-diethylaminophenyl)-3-(1',2'-dimethylindol-3'-yl)phthalide;3-[2-Methyl-4-(diethylamino)phenyl]-3-(1,2-dimethyl-3-indolyl)phthalide;MB3;3-[2-Methyl-4-(diethylamino)phenyl]-3-(1,2-dimethyl-3-indolyl)phthalide
2-(2'-Methyl-4'-diethylaminophenyl)-3-(1',2'-dimethylindol-3'-yl)phthalide;(2R,3S)-rel-4-Methylene-5-oxo-2-propyltetrahydrofuran-3-carboxylic acid | | CAS: | 36499-49-7 | | MF: | C29H30N2O2 | | MW: | 438.56 | | EINECS: | | | Product Categories: | Color Former;Color Former & Related Compounds;Functional Materials | | Mol File: | 36499-49-7.mol | ![3-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE Structure](CAS/GIF/36499-49-7.gif) |
| | 3-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE Chemical Properties |
| Melting point | 217 °C | | Boiling point | 627.3±55.0 °C(Predicted) | | density | 1.14 | | storage temp. | -20°C | | solubility | H2O: ≥10 mg/mL || DMSO: ≥20 mg/mL | | form | powder to crystal | | pka | 6.27±0.50(Predicted) | | color | White to Light yellow | | Water Solubility | H2O: ≥10mg/mL
DMSO: ≥20mg/mL | | InChI | 1S/C9H12O4/c1-3-4-6-7(8(10)11)5(2)9(12)13-6/h6-7H,2-4H2,1H3,(H,10,11)/t6-,7+/m1/s1 | | InChIKey | SRQUTZJZABSZRQ-RQJHMYQMSA-N | | SMILES | CCC[C@H]1OC(=O)C(=C)[C@@H]1C(O)=O |
| WGK Germany | nwg | | HS Code | 2933.99.8290 | | Storage Class | 11 - Combustible Solids |
| | 3-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE Usage And Synthesis |
| Uses | MB-3 has been used as a general control non-repressible 5 (GCN5) inhibitor:
- to study its effects on lamin A/C-associated pY19-Cav-2-mediated histone H3 acetylations
- to analyze its effects on the growth of Arabidopsis thaliana seedlings
- to study its effects on craniofacial chondrocyte maturation
| | Biological Activity | MB-3 can modify the gene expression in murine embryonic stem cells as well as yeast. It hinders the acetyltransferase activity of general control non-repressible 5 (GCN5) by binding to acetyl CoA pocket present in GCN5.', 'MB-3 is a Gcn5 H at (Histone Acetyltransferase) inhibitor; anti-inflammatory, anti-carcinogenic. |
| | 3-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE Preparation Products And Raw materials |
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