sPLA2 (Type IIA) Inhibitor Screening Assay Kit

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Company Name: Cayman Chemical Company  
Tel: 800-364-9897
Email: sales@caymanchem.com
sPLA2 (Type IIA) Inhibitor Screening Assay Kit Basic information
Product Name:sPLA2 (Type IIA) Inhibitor Screening Assay Kit
Synonyms:sPLA2 (Type IIA) Inhibitor Screening Assay Kit
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sPLA2 (Type IIA) Inhibitor Screening Assay Kit Structure
sPLA2 (Type IIA) Inhibitor Screening Assay Kit Chemical Properties
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sPLA2 (Type IIA) Inhibitor Screening Assay Kit Usage And Synthesis
DescriptionCayman’s sPLA2 (Type IIA) Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of human sPLA2 type IIA, a phospholipase that preferentially hydrolyzes PG and PE. The assay uses diheptanoyl thio-PE, a sulfur-containing analog of PE as a substrate. Upon hydrolysis by sPLA2 type IIA at the sn-2 position, the free thiol can be detected by the sPLA2 Assay Probe. This results in a product that can be easily quantified by measuring absorbance at a wavelength of 410 nm. A potent and reversible inhibitor, LY315920 (included in this kit as sPLA2 Control Inhibitor), inhibits the enzyme with an average IC50 value of approximately 22 nM.Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.WARNING This product is not for human or veterinary use.
sPLA2 (Type IIA) Inhibitor Screening Assay Kit Preparation Products And Raw materials
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