BETA-CASOMORPHIN (BOVINE)

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Products Intro: Product Name:β-Casomorphin (1-7), bovine
CAS:72122-62-4
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Products Intro: Product Name:β-Casomorphin (bovine)
CAS:72122-62-4
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Products Intro: Product Name:BETA-CASOMORPHIN (BOVINE)
CAS: 72122-62-4
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Products Intro: Product Name:β-Casomorphin (bovine)
CAS:72122-62-4
Purity:0.98 Package:1G;10G

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BETA-CASOMORPHIN (BOVINE) Basic information
Product Name:BETA-CASOMORPHIN (BOVINE)
Synonyms:H-TYR-PRO-PHE-PRO-GLY-PRO-ILE-OH;BETA-CASOMORPHIN-7;BETA-CASOMORPHIN-7 (BOVINE);BETA-CASOMORPHIN-7 (BOVINE) 4H2O;BETA-CASOMORPHIN (BOVINE);BETA-CASOMORPHIN (1-7), BOVINE;BETA CASOMORPHIN;L-TYR-PRO-PHE-PRO-GLY-PRO-ILE
CAS:72122-62-4
MF:C41H55N7O9
MW:789.92
EINECS:
Product Categories:peptide
Mol File:72122-62-4.mol
BETA-CASOMORPHIN (BOVINE) Structure
BETA-CASOMORPHIN (BOVINE) Chemical Properties
storage temp. -15°C
solubility Soluble in DMSO
form Solid
color White to off-white
SequenceTyr-Pro-Phe-Pro-Gly-Pro-Ile
Safety Information
MSDS Information
BETA-CASOMORPHIN (BOVINE) Usage And Synthesis
Usesβ-Casomorphin, bovine (β-Casomorphin-7 (bovine) ) is a opioid peptide with an IC50 of 14 μM in an Opioid receptors binding assay[1].
in vivo

β-Casomorphin, bovine (7.5×106 mol/day/kg ; i.g.; for 30 days) increases plasma insulin and decreased plasma glucagon of diabetic rats[3].
β-Casomorphin, bovine (7.5×106 mol/day/kg ; i.g.; for 30 days) alters the changes of SOD, GPx, T-AOC, MDA and H2O2 in the kidney of diabetic rats[3].
β-Casomorphin, bovine (7.5×106 mol/day/kg ; i.g.; for 30 days) reduces MDA (significantly) and H2O2 (non-significantly) level in the kidney compared to the diabetic rats[3].
β-Casomorphin, bovine (7.5×106 mol/day/kg ; i.g.; for 30 days) alleviates high glucose-induced decreasement in SOD and GPx activity, increasement in MDA contents in the NRK-52E cells[3].

Animal Model:Male Sprague-Dawley (SD) rats (200 g±10 g)[3]
Dosage:7.5×106 mol/day/kg
Administration:Oral gavage; for 30 days
Result:Increased plasma insulin and decreased plasma glucagon of diabetic rats.
References[1] Brantl V, et al. Opioid activities of beta-casomorphins. Life Sci. 1981 Apr 27;28(17):1903-9. DOI:10.1016/0024-3205(81)90297-6
[2] Zoghbi S, et al. β-casomorphin-7-7 regulates the secretion and expression of gastrointestinal mucins through a μ-opioid pathway. Am J Physiol Gastrointest Liver Physiol. 2006 Jun;290(6):G1105-13. DOI:10.1152/ajpgi.00455.2005
[3] Zhang W, et al. The protective effects of beta-casomorphin-7 against glucose -induced renal oxidative stress in vivo and vitro. PLoS One. 2013 May 3;8(5):e63472. DOI:10.1371/journal.pone.0063472
BETA-CASOMORPHIN (BOVINE) Preparation Products And Raw materials
Tag:BETA-CASOMORPHIN (BOVINE)(72122-62-4) Related Product Information
BETA-CASOMORPHIN BOVINE FRAGMENT 1-5 HYDROCHLORIDE H-TYR-PRO-PHE-VAL-GLU-PRO-ILE-OH BETA-CASOMORPHIN (1-6) (BOVINE) α-Casomorphin (1-2) BETA-CASOMORPHIN (1-3) BETA-CASOMORPHIN (1-5) AMIDE (BOVINE) BETA-CASOMORPHIN (1-4) (BOVINE) β-Casomorphin (1-4), amide (bovine) β-Casomorphin (1-2) amide BETA-CASOMORPHIN (1-3) AMIDE L-Tyr-L-Pro-L-Phe-L-Pro-Gly-L-Pro-OH β-Casomorphin (1-5), amide, bovine BETA-CGRP, HUMAN Glycyl-glycyl-L-valine Glycylglycyl-L-isoleucine H-PRO-VAL-OH H-PHE-PYRROLIDIDE (1-BENZYL-2-PYRROLIDIN-1-YLETHYL)AMINE