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| Product Name: | HUMAN IL-7 | | Synonyms: | HIL-7;INTERLEUKIN-7, HUMAN;INTERLEUKIN-7, HUMAN, RECOMBINANT;IL-7;IL-7, HUMAN;HUMAN PRE-B CELL FACTOR;HUMAN INTERLEUKIN-7;HUMAN LP-1 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![HUMAN IL-7 Structure]() |
| | HUMAN IL-7 Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder | | color | white to off-white | | biological source | rat | | Water Solubility | water: soluble 0.005-0.010mL |
| Hazard Codes | Xi | | Risk Statements | 36/38 | | Safety Statements | 26 | | WGK Germany | 3 | | Storage Class | 13 - Non Combustible Solids |
| | HUMAN IL-7 Usage And Synthesis |
| Uses | IL-7 is a hematopoietic growth factor, which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant rat IL-7 is a 15.0 kDa protein containing 130 amino acid residues. | | Biological Activity | IL-7 is a hematopoietic growth factor, which affects primarily early B and T cells. Recombinant r at IL-7 is a 15.0 kDa protein containing 130 amino acid residues. | | Description | Interleukin-7 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 152 amino acids and having a molecular mass of 17.4 kDa.
The IL-7 is purified by proprietary chromatographic techniques. | | Source | Escherichia Coli | | Background | IL-7 is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. |
| | HUMAN IL-7 Preparation Products And Raw materials |
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