TLCK

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TLCK Suppliers list
Company Name: J & K SCIENTIFIC LTD.  
Tel: 18210857532 18210857532
Email: jkinfo@jkchemical.com
Company Name: Spectrum Chemical Manufacturing Corp.  
Tel: 021-021-021-67601398-809-809-809 15221380277
Email: marketing_china@spectrumchemical.com
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Tel: 15026964105
Email: 2881489226@qq.com
Company Name: Greenherbs Science and Technology Development Co., Ltd.  
Tel: 010-61136123
Email: pub02@greenherbs.com.cn
Company Name: Hangzhou Peptidego Biotech Co.,Ltd.  
Tel: 0571-87213919 15967184799
Email: Eric@peptidego.com

TLCK manufacturers
TLCK Basic information
Product Name:TLCK
Synonyms:TOS-LYS-CHLOROMETHYLKETONE HCL;TOS-LYS-CMK HCL;TOSYL-L-LYSINE CHLOROMETHYLKETONE HCL;TOSYL-L-LYSYL-CHLOROMETHANE HCL;TLCK HYDROCHLORIDE;TLCK HCL;TLCK;p-N-(7-amino-1-chloro-2-oxohept-3-yl)toluenesulphonamide
CAS:4238-41-9
MF:C14H22Cl2N2O3S
MW:369.3
EINECS:224-199-0
Product Categories:
Mol File:4238-41-9.mol
TLCK Structure
TLCK Chemical Properties
Melting point ~165 °C (dec.)
storage temp. 2-8°C
solubility H2O: 50 mg/mL
form powder
color white to pink
Water Solubility Soluble in water
InChI1S/C14H21ClN2O3S.ClH/c1-11-5-7-12(8-6-11)21(19,20)17-13(14(18)10-15)4-2-3-9-16;/h5-8,13,17H,2-4,9-10,16H2,1H3;1H/t13-;/m0./s1
InChIKeyYFCUZWYIPBUQBD-ZOWNYOTGSA-N
SMILES[S](=O)(=O)(N[C@@H](CCCC[N+H3])C(=O)CCl)c1ccc(cc1)C.[Cl-]
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
RTECS XT5160000
F 10-21
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
TLCK Usage And Synthesis
UsesInhibitor of papain and trypsin
Biological ActivityCell permeable: no', 'EC50 = 80 μM blocking nitric oxide synthase induced by interferon-γ and lipopolysaccharides in macrophages', 'Primary Target
trypsin like proteases', 'Product does not compete with ATP.', 'Reversible: no
IC 50Caspase-3: 12.0 μM (IC50); Caspase-7: 19.3 μM (IC50); Caspase-6: 54.5 μM (IC50)
TLCK Preparation Products And Raw materials
Tag:TLCK(4238-41-9) Related Product Information
N-Tosyl-L-lysine chloromethyl ketone hydrochloride (TLCK) α-Chymotrypsin type VII-b biotinlabled a nd TLCK tr α-Chymotrypsin Tos-L-Lys-CMK·HCl 2-Heptanone A-CHYMOTRYPSIN TYPE VII TLCK TREATED TLCK,TLCK HYDROCHLORIDE,TLCK HCL