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| | 4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Basic information |
| Product Name: | 4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile | | Synonyms: | 4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile;4′-(2-butyl-4-chloro-5-hydroxyMethyliMidzole-1-ylMethyl)-
biphenyl-2-carbonitrile;2-(4-{[2-Butyl-4-chloro-5-(hydroxymethyl)imidazolyl]methyl} phenyl)benzene carbonitrile;Losartan Impurity 8;Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan;2-[4-[[2-butyl-4-chloro-5-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]benzonitrile;1'-Biphenyl]-2-carbonitrile;4'-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1 | | CAS: | 114772-55-3 | | MF: | C22H22ClN3O | | MW: | 379.88 | | EINECS: | | | Product Categories: | Losartan Potassium | | Mol File: | 114772-55-3.mol | ![4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Structure](CAS/20180713/GIF/114772-55-3.gif) |
| | 4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Chemical Properties |
| Melting point | 157-158°C | | Boiling point | 605.6±55.0 °C(Predicted) | | density | 1.19 | | storage temp. | Refrigerator | | solubility | DMSO (Slightly), Ethyl Acetate (Slightly) | | pka | 13.66±0.10(Predicted) | | form | Solid | | color | White to Off-White |
| | 4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Usage And Synthesis |
| Uses | Des[2’-(1H-tetrazol-5-yl)] 2-Cyanolosartan is a derivative of Losartan Potassium (L470500), a an angiotensin II antagonist and is commonly used to significantly reduce risk of new onset atrial fibrillation and associated stroke in high-risk patients. |
| | 4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Preparation Products And Raw materials |
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