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| | azetidin-3-ylmethanol hydrochloride Basic information |
| Product Name: | azetidin-3-ylmethanol hydrochloride | | Synonyms: | azetidin-3-ylmethanol hydrochloride;3-(Hydroxymethyl)azetidine hydrochloride;3-(HydroxyMethyl)azetidine 3;3-Azetidinemethanol hydrochloride;3-(HydroxyMethyl)azetidine HCl;(azetidine-3-yl)Methanol hcl;3-AzetidineMethanol,hydrochloride (1:1);Azetidin-3-yl-methanol hydrochloride 97% | | CAS: | 928038-44-2 | | MF: | C4H10ClNO | | MW: | 123.58 | | EINECS: | 815-099-3 | | Product Categories: | | | Mol File: | 928038-44-2.mol |  |
| | azetidin-3-ylmethanol hydrochloride Chemical Properties |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C | | form | powder to crystal | | color | White to Almost white | | Sensitive | Hygroscopic | | InChI | InChI=1S/C4H9NO.ClH/c6-3-4-1-5-2-4;/h4-6H,1-3H2;1H | | InChIKey | AQUVQGSNKVDBBF-UHFFFAOYSA-N | | SMILES | C1NCC1CO.Cl |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37-60 | | TSCA | No | | HazardClass | IRRITANT | | HS Code | 2905599890 |
| | azetidin-3-ylmethanol hydrochloride Usage And Synthesis |
| Uses | 3-Azetidinemethanol Hydrochloride is used in the synthesis of human rhinovirus inhibitors. | | Synthesis | General procedure for the synthesis of 3-methylhydroxyazetidine hydrochloride from 1-Boc-3-hydroxymethylazetidine: compound 1-Boc-3-hydroxymethylazetidine (0.100 g, 0.534 mmol) was dissolved in dichloromethane (2 mL), followed by the addition of a solution of hydrogen chloride in dioxane (1 mL, 4 M). The reaction mixture was stirred at room temperature for 20 hours. After completion of the reaction, the mixture was concentrated to afford the target product 3-methylhydroxyazetidine hydrochloride (white solid, 0.060 g, yield: 90.91%). | | References | [1] Patent: CN105732602, 2016, A. Location in patent: Paragraph 0410; 0411; 0412; 0413; 0414; 0415
[2] Patent: US2018/16252, 2018, A1. Location in patent: Paragraph 1112 |
| | azetidin-3-ylmethanol hydrochloride Preparation Products And Raw materials |
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