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| | N-Phenylquinoline-4-amine Basic information |
| Product Name: | N-Phenylquinoline-4-amine | | Synonyms: | 4-Anilinoquinoline;N-Phenylquinoline-4-amine;n-phenylquinolin-4-aMine;phenyl-quinolin-4-yl-amine;4-Quinolinamine, N-phenyl- | | CAS: | 30696-07-2 | | MF: | C15H12N2 | | MW: | 220.27 | | EINECS: | | | Product Categories: | | | Mol File: | 30696-07-2.mol |  |
| | N-Phenylquinoline-4-amine Chemical Properties |
| Melting point | 230 °C | | Boiling point | 380.2±17.0 °C(Predicted) | | density | 1.204±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C, protect from light | | pka | 6.70±0.13(Predicted) | | Appearance | Off-white to light yellow Solid |
| | N-Phenylquinoline-4-amine Usage And Synthesis |
| Synthesis | N-phenylquinolin-4-amine was prepared by adding aniline to 4-chloroquinoline ethanol solution under microwave irradiation at 165°C.
Experiment steps：To a solution of 4-chloroquinoline (350 mg, 2.14 mmol) in ethanol (3 ml), aniline (996 mg, 10.7 mmol) was added and the mixture was reacted at 165 °C for 3 hours under microwave radiation. The reaction mixture was concentrated in vacuo, aqueous sodium carbonate (25 ml) was added and this was then extracted using dichloromethane (3×30 ml). The organic extracts were collected, dried using magnesium sulphate, concentrated in vacuo and the resulting residue was purified by flash column chromatography eluting with 2% methanol in dichloromethane to give N-phenylquinolin-4-amine as a colourless solid (42 mg, 9%). |
| | N-Phenylquinoline-4-amine Preparation Products And Raw materials |
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