(3S,αR)-3-[[[4-[(R)-3-Amino-3-carboxypropoxy]phenyl]-[(Z)-hydroxyimino]acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-1-azetidineacetic acid 基本信息
| 中文名称 | (3S,αR)-3-[[[4-[(R)-3-Amino-3-carboxypropoxy]phenyl]-[(Z)-hydroxyimino]acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-1-azetidineacetic acid |
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| 中文同义词 | 化合物 T25876;诺卡菌素 A;(3S,ΑR)-3-[[[4-[(R)-3-AMINO-3-CARBOXYPROPOXY]PHENYL]-[(Z)-HYDROXYIMINO]ACETYL]AMINO]-Α-(4-HYDROXYPHENYL)-2-OXO-1-AZETIDINEACETIC ACID;化合物 Nocardicin A |
| 英文名称 | (3S,αR)-3-[[[4-[(R)-3-Amino-3-carboxypropoxy]phenyl]-[(Z)-hydroxyimino]acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-1-azetidineacetic acid |
| 英文同义词 | FR-1923C;Nocardicin A;(αR,3S)-3-[[(2Z)-2-[4-[(3R)-3-AMino-3-carboxypropoxy]phenyl]-2-(hydroxyiMino)acetyl]aMino]-α-(4-hydroxyphenyl)-2-oxo-1-azetidineacetic Acid;(3S,αR)-3-[[[4-[(R)-3-Amino-3-carboxypropoxy]phenyl]-[(Z)-hydroxyimino]acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-1-azetidineacetic acid;(3S,αR)-3β-[[[4-[(3R)-3-Amino-3-carboxypropoxy]phenyl][(Z)-hydroxyimino]acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-1-azetidineacetic acid;Antibiotic FR-1923;FR-1923;1-Azetidineacetic acid, 3-[[(2Z)-2-[4-[(3R)-3-amino-3-carboxypropoxy]phenyl]-2-(hydroxyimino)acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-, (αR,3S)- |
| CAS号 | 39391-39-4 |
| 分子式 | C23H24N4O9 |
| 分子量 | 500.45806 |
| EINECS号 | |
| 相关类别 | Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals |
| Mol文件 | 39391-39-4.mol |
| 结构式 | ![(3S,αR)-3-[[[4-[(R)-3-Amino-3-carboxypropoxy]phenyl]-[(Z)-hydroxyimino]acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-1-azetidineacetic acid 结构式](CAS/GIF/39391-39-4.gif) |
(3S,αR)-3-[[[4-[(R)-3-Amino-3-carboxypropoxy]phenyl]-[(Z)-hydroxyimino]acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-1-azetidineacetic acid 性质
| 熔点 | 214-216° (dec) |
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| 比旋光度 | D25 -135° (for the sodium salt) |
| 沸点 | 591.34°C (rough estimate) |
| 密度 | 1.4360 (rough estimate) |
| 折射率 | 1.6500 (estimate) |
| 酸度系数(pKa) | 2.18±0.10(Predicted) |
| 颜色 | 针状晶体 |
(3S,αR)-3-[[[4-[(R)-3-Amino-3-carboxypropoxy]phenyl]-[(Z)-hydroxyimino]acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-1-azetidineacetic acid 用途与合成方法
类别
有毒物品毒性分级
中毒急性毒性
腹腔-大鼠 LD50: 2600 毫克/公斤; 腹腔-小鼠 LD50: 2500 毫克/公斤可燃性危险特性
可燃; 燃烧产生有毒氮氧化物烟雾储运特性
库房通风低温干燥灭火剂
干粉,泡沫,沙土,二氧化碳, 雾状水安全信息
| 毒性 | LD50 in male mice, rats (mg/kg): >8000 orally; >2000 i.v.; 2500, 2600 i.p. (Aoki) |
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