(Z)-7-[2β-[(1E,3R)-3-Hydroxy-4-(3-chlorophenoxy)-1-butenyl]-3α,5α-dihydroxycyclopentane-1α-yl]-5-heptenoic acid methyl ester

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(Z)-7-[2β-[(1E,3R)-3-Hydroxy-4-(3-chlorophenoxy)-1-butenyl]-3α,5α-dihydroxycyclopentane-1α-yl]-5-heptenoic acid methyl ester Suppliers list
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(Z)-7-[2β-[(1E,3R)-3-Hydroxy-4-(3-chlorophenoxy)-1-butenyl]-3α,5α-dihydroxycyclopentane-1α-yl]-5-heptenoic acid methyl ester manufacturers
(Z)-7-[2β-[(1E,3R)-3-Hydroxy-4-(3-chlorophenoxy)-1-butenyl]-3α,5α-dihydroxycyclopentane-1α-yl]-5-heptenoic acid methyl ester Basic information
Product Name:(Z)-7-[2β-[(1E,3R)-3-Hydroxy-4-(3-chlorophenoxy)-1-butenyl]-3α,5α-dihydroxycyclopentane-1α-yl]-5-heptenoic acid methyl ester
Synonyms:(5Z,9S,11R,13E,15R)-9,11,15-Trihydroxy-16-(3-chlorophenoxy)-17,18,19,20-tetranorprosta-5,13-diene-1-oic acid methyl ester;(Z)-7-[(1R)-2β-[(E,R)-4-(3-Chlorophenoxy)-3-hydroxy-1-butenyl]-3α,5α-dihydroxycyclopentan-1α-yl]-5-heptenoic acid methyl ester;(Z)-7-[2β-[(1E,3R)-3-Hydroxy-4-(3-chlorophenoxy)-1-butenyl]-3α,5α-dihydroxycyclopentane-1α-yl]-5-heptenoic acid methyl ester;(+)-Cloprostenol methyl ester;(+)-Cloprostenol methyl ester Exclusive;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, methyl ester, (5Z)-;(+)Cloprostenol methyl ester,(+) Cloprostenol methyl ester
CAS:56687-85-5
MF:C23H31ClO6
MW:438.94
EINECS:
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Mol File:56687-85-5.mol
(Z)-7-[2β-[(1E,3R)-3-Hydroxy-4-(3-chlorophenoxy)-1-butenyl]-3α,5α-dihydroxycyclopentane-1α-yl]-5-heptenoic acid methyl ester Structure
(Z)-7-[2β-[(1E,3R)-3-Hydroxy-4-(3-chlorophenoxy)-1-butenyl]-3α,5α-dihydroxycyclopentane-1α-yl]-5-heptenoic acid methyl ester Chemical Properties
Boiling point 585.5±50.0 °C(Predicted)
density 1.264±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 50 mg/ml; DMSO: 100 mg/ml; Ethanol: 100 mg/ml; PBS (pH 7.2): 10 mg/ml
pka13.41±0.20(Predicted)
Safety Information
MSDS Information
(Z)-7-[2β-[(1E,3R)-3-Hydroxy-4-(3-chlorophenoxy)-1-butenyl]-3α,5α-dihydroxycyclopentane-1α-yl]-5-heptenoic acid methyl ester Usage And Synthesis
Description(+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. It is 200 times and 100 times more potent than PGF2α in terminating pregnancy in hamsters and rats, respectively, without the side effects associated with PGF2α. Cloprostenol is also used in veterinary medicine as a luteolytic agent for the induction of estrus and the treatment of reproductive disorders in cattle, swine, and horses. (+)-Cloprostenol methyl ester is a more lipid soluble form of cloprostenol, which may be more amenable for certain formulations.
Uses(+)-Cloprostenol methyl ester is a 11,13-Dienone analog of cloprostenol (HY-107381)[1].
References[1] Vostrikov, et al. New 11,13-Dienone Analog of Cloprostenol. Russian Journal of Organic Chemistry, 2019, 55(10), 1465–1468.
(Z)-7-[2β-[(1E,3R)-3-Hydroxy-4-(3-chlorophenoxy)-1-butenyl]-3α,5α-dihydroxycyclopentane-1α-yl]-5-heptenoic acid methyl ester Preparation Products And Raw materials
Tag:(Z)-7-[2β-[(1E,3R)-3-Hydroxy-4-(3-chlorophenoxy)-1-butenyl]-3α,5α-dihydroxycyclopentane-1α-yl]-5-heptenoic acid methyl ester(56687-85-5) Related Product Information
(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-(S)-3-hydroxy-5-phenyl-pent-1-enyl)-cyclopentyl]-hept-5-enoic acid methyl ester (Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester (+)-Cloprostenol isopropyl ester (+)-Cloprostenol methyl amide (+)-Cloprostenol 5-(Hydroxymethyl)-2'-deoxycytidine