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| | AKT3 (AB-1) POLYCLONAL ANTIBODY Basic information |
| Product Name: | AKT3 (AB-1) POLYCLONAL ANTIBODY | | Synonyms: | AKT3 (AB-1) POLYCLONAL ANTIBODY;Anti-AKT2, (N-terminal) antibody produced in rabbit;Anti-AKT2 antibody produced in rabbit;Monoclonal Anti-AKT1 antibody produced in mouse;Anti-AKT2, C-Terminal antibody produced in rabbit;Anti-AKT1 antibody produced in goat;Anti-AKT, C-Terminal antibody produced in rabbit;Anti-AKT, N-Terminal antibody produced in rabbit | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | Elisa Kit-plant ELISA Kit | | Mol File: | Mol File | ![AKT3 (AB-1) POLYCLONAL ANTIBODY Structure]() |
| | AKT3 (AB-1) POLYCLONAL ANTIBODY Chemical Properties |
| storage temp. | -70°C | | form | buffered aqueous solution | | biological source | rabbit | | Specific Activity | 103-139nmol/min·mg |
| Hazard Codes | T | | Risk Statements | 61 | | Safety Statements | 53-45 | | WGK Germany | 1 | | Storage Class | 10 - Combustible liquids |
| | AKT3 (AB-1) POLYCLONAL ANTIBODY Usage And Synthesis |
| Uses | v-akt murine thymoma viral oncogene homolog 1 (AKT1) is a Ser/Thr protein kinase, and is also called protein kinase B (PKB). This protein is activated when it is phosphorylated at serine 473 and threonine 308. This gene is localized on human chromosome 14q32.32. | | General Description | v-akt murine thymoma viral oncogene homolog 1 (AKT1) is a Ser/Thr protein kinase, and is also called protein kinase B (PKB). This protein is activated when it is phosphorylated at serine 473 and threonine 308. This gene is localized on human chromosome 14q32.32. | | Biochem/physiol Actions | v-akt murine thymoma viral oncogene homolog 1 (AKT1) is responsible for the phosphorylation and cytoplasmic localization of CKDN1A (cyclin-dependent kinase (CDK) inhibitor 1, also referred to as p21). However, p21 is one of the CDKNs which normally resides in the nucleus and its cytoplasmic localization, mediated by AKT1, is common to various cancers where it suppresses proteins essential for apoptosis. Studies show that up-regulation of AKT1 serves as a poor prognostic marker in breast cancer, which however, depends upon factors including population, hormone receptor status, and hormonal or trastuzumab therapy status. |
| | AKT3 (AB-1) POLYCLONAL ANTIBODY Preparation Products And Raw materials |
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