| Company Name: |
China Langchem Inc.
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| Tel: |
0086-21-58956006 |
| Email: |
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| Products Intro: |
Product Name:3-phenylisothiazol-5-amine
CAS:14208-52-7
Purity:99% HPLC Package:10g;100G;1KG
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| Company Name: |
DKMbiochem.Co. Ltd
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| Tel: |
15901859516 |
| Email: |
sales@DKMbiochem.com |
| Products Intro: |
Product Name:3-phenylisothiazol-5-aMine
CAS:14208-52-7
Purity:98% Package:5g,10g,50g,100G
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| | 3-Phenylisothiazol-5-amine Basic information |
| | 3-Phenylisothiazol-5-amine Chemical Properties |
| Melting point | 163 °C | | Boiling point | 269.8±38.0 °C(Predicted) | | density | 1.261±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | pka | 6.88±0.20(Predicted) |
| | 3-Phenylisothiazol-5-amine Usage And Synthesis |
| Synthesis | In a sealed tube, (Z)-3-amino-3-phenylacrylonitrile (95 mg, 0.660 mmol) was dissolved in a solvent mixture of EtOH (1.0 mL) and THF (1.0 mL). H2S gas was bubbled into the solution for 5 min. Subsequently, the reaction mixture was stirred at 90 °C for 20 hours. Upon completion of the reaction, the mixture was concentrated under reduced pressure. The concentrated residue was dissolved in MeOH (2.0 mL) and H2O2 (30%, 0.5 mL) was added. The reaction was terminated by stirring at room temperature for 2 min. The mixture was again concentrated under reduced pressure. Finally, the residue was purified by high performance liquid chromatography (HPLC) to afford the target product 3-phenylisothiazol-5-amine (22 mg). | | References | [1] Patent: US2013/131040, 2013, A1. Location in patent: Paragraph 1140 |
| | 3-Phenylisothiazol-5-amine Preparation Products And Raw materials |
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