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| | 17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide Basic information |
| Product Name: | 17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide | | Synonyms: | 17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide;N-Cyclopropyl Methyl Bimatoprost;cyclopropylmethylbimatoprost;17-phenyl trinor Prostaglandin F2.alpha. cyclopropyl methyl amide;17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide Exclusive;N-(cyclopropylmethyl)-7-[3,5-dihydroxy-2-(3-hydroxy-5-phenylpent-1-enyl)cyclopentyl]hept-5-enamide;5-Heptenamide, N-(cyclopropylmethyl)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-, (5Z)-;Sparsentan Impurity 16 | | CAS: | 1138395-10-4 | | MF: | C27H39NO4 | | MW: | 441.6 | | EINECS: | | | Product Categories: | | | Mol File: | 1138395-10-4.mol |  |
| | 17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Acetonitrile: 3 mg/ml; DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): .25 mg/ml | | form | A crystalline solid | | Cosmetics Ingredients Functions | ANTIOXIDANT |
| | 17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide Usage And Synthesis |
| Description | Prostaglandin F2α (PGF2α) activates the FP receptor, promoting smooth muscle contraction and luteolysis. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. It is produced in vivo by the hydrolysis of 17-phenyl trinor PGF2α ethyl amide. 17-phenyl trinor PGF2α ethyl amide is used to reduce intraocular pressure related to glaucoma. 17-phenyl trinor PGF2α cyclopropyl methyl amide is a lipophilic analog of 17-phenyl trinor PGF2α. Amides of PGs may serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid. | | Uses | N-Cyclopropyl Methyl Bimatoprostis a useful reagent for developing methods for treating epithelial-related conditions including hair loss. N-Cyclopropyl Methyl Bimatoprostis also an analog ofBimatoprost (B386800), an synthetic prostamide and structurally related to prostaglandin F2α. | | References | [1] CARL B. CAMRAS MD , PHD Edward M B M Nehal Patel MD, PHD , et al. Detection of the free acid of bimatoprost in aqueous humor samples from human eyes treated with bimatoprost before cataract surgery[J]. Ophthalmology, 2004, 111 12: Pages 2193-2198. DOI: 10.1016/j.ophtha.2004.06.028 |
| | 17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide Preparation Products And Raw materials |
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