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amyjet
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4006800868;027-59626688 18771149750 |
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sales@amyjet.com |
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Product Name:iNOS Polyclonal Antibody
Package:1mL
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| Company Name: |
Cayman Chemical Company
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| Tel: |
800-364-9897 |
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sales@caymanchem.com |
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Product Name:iNOS Polyclonal Antibody
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| Company Name: |
Enzo Biochem Inc
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| Tel: |
Enzo Biochem Inc. 13797054060 |
| Email: |
Enzoname@qq.com |
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Product Name:iNOS polyclonal antibody
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| Company Name: |
Neobioscience Co., Ltd.
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| Tel: |
4006-800-892 |
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info@neobioscience.com |
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Product Name:iNOS polyclonal antibody
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| Company Name: |
Proteintech China
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| Tel: |
027-87531629 |
| Email: |
Proteintech-CN@ptglab.com |
| Products Intro: |
Product Name:iNOS Polyclonal antibody
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| | iNOS Polyclonal Antibody Basic information |
| | iNOS Polyclonal Antibody Chemical Properties |
| | iNOS Polyclonal Antibody Usage And Synthesis |
| Description | Nitric Oxide Synthase (NOS) catalyzes the biosynthesis of nitric oxide from L-arginine. Constitutively expressed NOS is found in brain (nNOS) and endothelial cells (eNOS). iNOS is a soluble enzyme found in a variety of tissues including macrophages, hepatocytes, vascular smooth muscle cells, and chondrocytes. iNOS expression is increased by a variety of factors including LPS, IFN-γ, Il-1β, and TNF-α, whereas expression is deceased by dexamethasone. The enzyme has been cloned from several species including mouse, rat, and human with homology of at least 80% between these species. The calculated molecular weight of the protein from the deduced amino acid sequence is 130,000 - 131,000. | | References | [1] R G KNOWLES S M. Nitric oxide synthases in mammals.[J]. Biochemical Journal, 1994, 298 ( Pt 2): 249-258. DOI: 10.1042/bj2980249
[2] D A GELLER T R B. Molecular biology of nitric oxide synthases.[J]. Cancer and Metastasis Reviews, 1998, 17 1: 7-23. DOI: 10.1023/a:1005940202801
[3] R. LORSBACH. Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for the synergy between interferon-gamma and lipopolysaccharide.[J]. The Journal of Biological Chemistry, 1993, 16 1: 1908-1913. DOI: 10.1016/s0021-9258(18)53940-5
[4] J L BALLIGAND. Cytokine-inducible nitric oxide synthase (iNOS) expression in cardiac myocytes. Characterization and regulation of iNOS expression and detection of iNOS activity in single cardiac myocytes in vitro.[J]. The Journal of Biological Chemistry, 1994, 269 44: 27580-27588.
[5] H H SCHMIDT. Regulation and subcellular location of nitrogen oxide synthases in RAW264.7 macrophages.[J]. Molecular Pharmacology, 1992, 41 4: 615-624.
[6] T OGURA H E. Nitric oxide synthase expression in human neuroblastoma cell line induced by cytokines.[J]. Neuroreport, 1996, 7 4: 853-856. DOI: 10.1097/00001756-199603220-00003
[7] G WALKER D K J Pfeilschifter. Mechanisms of suppression of inducible nitric-oxide synthase (iNOS) expression in interferon (IFN)-gamma-stimulated RAW 264.7 cells by dexamethasone. Evidence for glucocorticoid-induced degradation of iNOS protein by calpain as a key step in post-transcriptional regulation.[J]. The Journal of Biological Chemistry, 1997, 272 26: 16679-16687. DOI: 10.1074/jbc.272.26.16679
[8] ALEXANDER A CHUMANEVICH. Repurposing the anti-malarial drug, quinacrine: new anti-colitis properties.[J]. Oncotarget, 2016, 7 33: 52928-52939. DOI: 10.18632/oncotarget.10608
[9] CHIEN-CHENG CHEN. Berberine protects against neuronal damage via suppression of glia-mediated inflammation in traumatic brain injury.[J]. PLoS ONE, 2014: e115694. DOI: 10.1371/journal.pone.0115694
[10] JAMES D NICHOLSON. PGJ(2) provides prolonged CNS stroke protection by reducing white matter edema.[J]. PLoS ONE, 2012: e50021. DOI: 10.1371/journal.pone.0050021
[11] CRISTIANO MARCELO ESPINOLA CARVALHO. Inducible nitric oxide synthase in heart tissue and nitric oxide in serum of Trypanosoma cruzi-infected rhesus monkeys: association with heart injury.[J]. PLoS Neglected Tropical Diseases, 2012, 6 5: e1644. DOI: 10.1371/journal.pntd.0001644
[12] HEI-JEN HUANG. Exendin-4 protected against cognitive dysfunction in hyperglycemic mice receiving an intrahippocampal lipopolysaccharide injection.[J]. PLoS ONE, 2012: e39656. DOI: 10.1371/journal.pone.0039656 |
| | iNOS Polyclonal Antibody Preparation Products And Raw materials |
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