2'-O-t-ButyldiMethylsilyl adenosine

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2'-O-t-ButyldiMethylsilyl adenosine manufacturers
2'-O-t-ButyldiMethylsilyl adenosine Basic information
Product Name:2'-O-t-ButyldiMethylsilyl adenosine
Synonyms:2'-O-TBDMS adenosine;2'-O-t-ButyldiMethylsilyl adenosine;Adenosine, 2'-O-[(1,1-dimethylethyl)dimethylsilyl]- (9CI);2'-O-TBDMS-adenosine
CAS:69504-13-8
MF:C16H27N5O4Si
MW:381.5
EINECS:
Product Categories:Nucleosides-2'-O-TBDMS Nucleosides
Mol File:69504-13-8.mol
2'-O-t-ButyldiMethylsilyl adenosine Structure
2'-O-t-ButyldiMethylsilyl adenosine Chemical Properties
Boiling point 572.2±60.0 °C(Predicted)
density 1.39±0.1 g/cm3(Predicted)
pka13.13±0.70(Predicted)
Safety Information
MSDS Information
2'-O-t-ButyldiMethylsilyl adenosine Usage And Synthesis
Uses2’-O-t-Butyldimethylsilyladenosine is a adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
References[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
2'-O-t-ButyldiMethylsilyl adenosine Preparation Products And Raw materials
Tag:2'-O-t-ButyldiMethylsilyl adenosine(69504-13-8) Related Product Information
Uridine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]- 2'-O-(tert-butyldimethylsilyl)cytidine 3'-O-tert-Butyldimethylsilyladenosine 2'-O-(tert-butyldiMethylsilyl)uridine 2'-TBDMS-5-Me-rU 2'-O-(tert-butyl-dimethyl-silanyl)-guanosine Guanosine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]- (9CI) INDEX NAME NOT YET ASSIGNED