2-Propenoic acid, 3-(4-hydroxy-3-Methoxyphenyl)-, ethyl ester, (2E)-

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2-Propenoic acid, 3-(4-hydroxy-3-Methoxyphenyl)-, ethyl ester, (2E)- Basic information
Product Name:2-Propenoic acid, 3-(4-hydroxy-3-Methoxyphenyl)-, ethyl ester, (2E)-
Synonyms:2-Propenoic acid, 3-(4-hydroxy-3-Methoxyphenyl)-, ethyl ester, (2E)-;Ethyl (E)-ferulate;trans-Ferulic acid ethyl ester;2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, ethyl ester, (E)-;Ethyl (2E)-3-(4-hydroxy-3-methoxyphenyl)-2-propenoate
CAS:28028-62-8
MF:C12H14O4
MW:222.24
EINECS:
Product Categories:
Mol File:28028-62-8.mol
2-Propenoic acid, 3-(4-hydroxy-3-Methoxyphenyl)-, ethyl ester, (2E)- Structure
2-Propenoic acid, 3-(4-hydroxy-3-Methoxyphenyl)-, ethyl ester, (2E)- Chemical Properties
Safety Information
MSDS Information
2-Propenoic acid, 3-(4-hydroxy-3-Methoxyphenyl)-, ethyl ester, (2E)- Usage And Synthesis
UsesEthyl (E)-ferulate is an AMPK/Nrf2 signaling pathway activator that can reduce lipopolysaccharide (HY-D1056)-induced acute lung injury. Additionally, Ethyl (E)-ferulate exhibits free radical scavenging properties, providing anti-inflammatory, antioxidant, neuroprotective, and sunscreen effects. Ethyl (E)-ferulate holds promise for research in the fields of inflammation and neurodegenerative diseases[1][2][3].
References[1] Wu YX, et al. Ethyl ferulate protects against lipopolysaccharide-induced acute lung injury by activating AMPK/Nrf2 signaling pathway. Acta Pharmacol Sin. 2021 Dec;42(12):2069-2081. DOI:10.1038/s41401-021-00742-0
[2] Nazaré A C, et al. Ethyl ferulate, a component with anti-inflammatory properties for emulsion-based creams[J]. Molecules, 2014, 19(6): 8124-8139. DOI:10.3390/molecules19068124
[3] Cunha FVM, et al. Systematic review and technological prospection: ethyl ferulate, a phenylpropanoid with antioxidant and neuroprotective actions. Expert Opin Ther Pat. 2019 Feb;29(2):73-83. DOI:10.1080/13543776.2019.1568410
2-Propenoic acid, 3-(4-hydroxy-3-Methoxyphenyl)-, ethyl ester, (2E)- Preparation Products And Raw materials
Tag:2-Propenoic acid, 3-(4-hydroxy-3-Methoxyphenyl)-, ethyl ester, (2E)-(28028-62-8) Related Product Information
Ferulic Acid trans-Ferulic acid 4-Hydroxy-3-methoxycinnamaldehyde CONIFERYL ALCOHOL Ethyl 4-hydroxy-3-methoxycinnamate 4-Hydroxy-3-methoxycinnamaldehyde