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Haoyuan Chemexpress Co., Ltd.
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| Products Intro: |
Product Name:ortho-iodoHoechst 33258
CAS:158013-41-3
Purity:>98% Package:3500RMB/5mg
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| Company Name: |
MedChemexpress LLC
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| Tel: |
021-58955995 |
| Email: |
sales@medchemexpress.cn |
| Products Intro: |
Product Name:ortho-iodoHoechst 33258
CAS:158013-41-3
Purity:>98% Package:3500RMB/5mg
|
| Company Name: |
SPIRO PHARMA
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| Tel: |
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| Email: |
eric_feng1954@126.com |
| Products Intro: |
Product Name:ortho-iodoHoechst 33258
CAS:158013-41-3
Purity:95% -98%HPLC Package:1GR;10GR;50GR;100GR;250GR;500GR;1KG;5KG;10KG;100KG
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| | ortho-iodoHoechst 33258 Basic information |
| Product Name: | ortho-iodoHoechst 33258 | | Synonyms: | IODOHOECHST 33258, BR;ortho-iodoHoechst 33258, BR;ortho-iodoHoechst 33258;2,6'-Bi-1H-benzimidazole, 2'-(2-iodophenyl)-6-(4-methyl-1-piperazinyl)-;2-(2-iodophenyl)-6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazole;2'-(2-Iodophenyl)-6-(4-methylpiperazin-1-yl)-1H,3'H-2,5'-bibenzo[d]imidazole | | CAS: | 158013-41-3 | | MF: | C25H23IN6 | | MW: | 534.39 | | EINECS: | | | Product Categories: | | | Mol File: | 158013-41-3.mol |  |
| | ortho-iodoHoechst 33258 Chemical Properties |
| Boiling point | 744.4±70.0 °C(Predicted) | | density | 1.587±0.06 g/cm3(Predicted) | | solubility | 25℃: DMSO or water Protect from light | | form | Powder | | pka | 10.58±0.10(Predicted) | | color | Pink to red | | Appearance | Solid Powder |
| | ortho-iodoHoechst 33258 Usage And Synthesis |
| Description | Ortho-iodoHoechst 33258, an iodinated DNA-binding bibenzimidazole, is a cell dye for DNA quantitation which sensitizes DNA and cells to UVA. | | Uses | ortho-iodoHoechst 33258 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1]. | | References | [1] a b c "Hoechst Stains". Invitrogren (Molecular Probes).
[2] Latt SA, Stetten G, Juergens LA, Recent developments in the detection of deoxyribonucleic acid synthesis by 33258 Hoechst fluorescence. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 23 (7): 493-505. DOI:10.1177/23.7.1095650
[3] Portugal J, Waring MJ. Assignment of DNA binding sites for 4',6-diamidine-2-phenylindole and bisbenzimide (Hoechst 33258). A comparative footprinting study. Biochimica et Biophysica Acta 949 (2): 158-68. DOI:10.1016/0167-4781(88)90079-6 |
| | ortho-iodoHoechst 33258 Preparation Products And Raw materials |
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