9-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-2,3,4,4a,9,9a-hexahydro-1H-carbazole

9-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-2,3,4,4a,9,9a-hexahydro-1H-carbazole Suppliers list

9-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-2,3,4,4a,9,9a-hexahydro-1H-carbazole Basic information

Product Name:	9-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-2,3,4,4a,9,9a-hexahydro-1H-carbazole
Synonyms:	9-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-2,3,4,4a,9,9a-hexahydro-1H-carbazole;9-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,2,3,4,4a,9a-hexahydrocarbazole;CP-352664
CAS:	1097883-05-0
MF:	C18H18N4
MW:	290.36232
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Mol File:	1097883-05-0.mol

9-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-2,3,4,4a,9,9a-hexahydro-1H-carbazole Chemical Properties

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9-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-2,3,4,4a,9,9a-hexahydro-1H-carbazole Usage And Synthesis

Uses	CP-352664 is a JAK inhibitor. CP-352664 has a inhibitoinhibits JAK3 with an EC50 value of 210 nM. CP-352664 is promising for research of organ transplant rejection and autoimmune disorders such as rheumatoid arthritis[1].
References	[1] Flanagan ME, et al. Discovery of CP-690,550: a potent and selective Janus kinase (JAK) inhibitor for the treatment of autoimmune diseases and organ transplant rejection. J Med Chem. 2010 Dec 23;53(24):8468-84. DOI:10.1021/jm1004286

9-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-2,3,4,4a,9,9a-hexahydro-1H-carbazole Preparation Products And Raw materials

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