(S)-5-Methoxy-N-propyl-N-(2-(thiophen-2-yl)ethyl)-1,2,3,4-tetrahydronaphthalen-2-aMine

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(S)-5-Methoxy-N-propyl-N-(2-(thiophen-2-yl)ethyl)-1,2,3,4-tetrahydronaphthalen-2-aMine Basic information
Product Name:(S)-5-Methoxy-N-propyl-N-(2-(thiophen-2-yl)ethyl)-1,2,3,4-tetrahydronaphthalen-2-aMine
Synonyms:(2S)-5-methoxy-N-propyl-N-(2-thiophen-2-ylethyl)-1,2,3,4-tetrahydronaphthalen-2-amine;Rotigotine USP RC H;(S)-5-methoxy-N-propyl-N-(2'-(thien-2-yl-)ethyl)-tetralin-2-amine;(S)-5-Methoxy-N-propyl-N-(2-(thiophen-2-yl)ethyl)-1,2,3,4-tetrahydronaphthalen-2-aMine;Rotigotine USP Related Compound H;Rotigotine Impurity 5(Rotigotine USP RC H);2-Thiopheneethanamine, N-propyl-N-[(2S)-1,2,3,4-tetrahydro-5-methoxy-2-naphthalenyl]-;5’-Deshydroxy-5’-methoxy Rotigotine
CAS:1148154-91-9
MF:C20H27NOS
MW:329.5
EINECS:
Product Categories:
Mol File:1148154-91-9.mol
(S)-5-Methoxy-N-propyl-N-(2-(thiophen-2-yl)ethyl)-1,2,3,4-tetrahydronaphthalen-2-aMine Structure
(S)-5-Methoxy-N-propyl-N-(2-(thiophen-2-yl)ethyl)-1,2,3,4-tetrahydronaphthalen-2-aMine Chemical Properties
Boiling point 473.5±45.0 °C(Predicted)
density 1.10±0.1 g/cm3(Predicted)
storage temp. 2-8°C
pka8.92±0.20(Predicted)
Major Applicationpharmaceutical
InChI1S/C20H27NOS/c1-3-12-21(13-11-18-7-5-14-23-18)17-9-10-19-16(15-17)6-4-8-20(19)22-2/h4-8,14,17H,3,9-13,15H2,1-2H3/t17-/m0/s1
InChIKeyAXOQYAWBBDSEMG-KRWDZBQOSA-N
SMILES[s]1c(ccc1)CCN([C@H]2CCc3c(cccc3OC)C2)CCC
Safety Information
WGK Germany WGK 3
HS Code 2934990002
Storage Class10 - Combustible liquids
MSDS Information
(S)-5-Methoxy-N-propyl-N-(2-(thiophen-2-yl)ethyl)-1,2,3,4-tetrahydronaphthalen-2-aMine Usage And Synthesis
Uses5’-Deshydroxy-5’-methoxy Rotigotine is an impurity of Rotigotine (R700700). Rotigotine is a non-ergot dopamine agonist drug and is indicated for the treatment of Parkinson’s disease.
(S)-5-Methoxy-N-propyl-N-(2-(thiophen-2-yl)ethyl)-1,2,3,4-tetrahydronaphthalen-2-aMine Preparation Products And Raw materials
Raw materials2-Thiopheneethanamine, N-[(2S)-1,2,3,4-tetrahydro-5-methoxy-2-naphthalenyl]--->Benzenesulfonic acid, 2-nitro-, 2-(2-thienyl)ethyl ester-->1-Iodopropane-->(S)-1,2,3,4-tetrahydro-5-methoxy-N-propyl-2-Naphthalenamine(Rotigotine)
Tag:(S)-5-Methoxy-N-propyl-N-(2-(thiophen-2-yl)ethyl)-1,2,3,4-tetrahydronaphthalen-2-aMine(1148154-91-9) Related Product Information