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| | D-erythro-sphingosine-1-phosphate (C20 base) Basic information |
| Product Name: | D-erythro-sphingosine-1-phosphate (C20 base) | | Synonyms: | D-erythro-sphingosine-1-phosphate (C20 base);D-ERYTHRO-SPHINGOSINE-1-PHOSPHATE (C20 BASE);SPHINGOSINE-1-PHOSPHATE (D20:1);Sphingosine-1-Phosphate (d20:1);4-Eicosene-1,3-diol, 2-amino-, 1-(dihydrogen phosphate), (2S,3R,4E)- | | CAS: | 799812-75-2 | | MF: | C20H42NO5P | | MW: | 407.52 | | EINECS: | | | Product Categories: | | | Mol File: | 799812-75-2.mol |  |
| | D-erythro-sphingosine-1-phosphate (C20 base) Chemical Properties |
| Boiling point | 569.4±60.0 °C(Predicted) | | density | 1.073±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | pka | 1.76±0.10(Predicted) | | form | powder | | InChI | 1S/C20H42NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)19(21)18-26-27(23,24)25/h16-17,19-20,22H,2-15,18,21H2,1H3,(H2,23,24,25)/b17-16+/t19-,20+/m0/s1 | | InChIKey | YUUWWSOTAGQJFW-YIVRLKKSSA-N | | SMILES | [H][C@](/C=C/CCCCCCCCCCCCCCC)(O)[C@]([NH3+])([H])COP([O-])(O)=O |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | D-erythro-sphingosine-1-phosphate (C20 base) Usage And Synthesis |
| Uses | D-erythro-Sphingosine-C20-1-phosphate is a growth factor-like lipid having a phosphate group. The concentration of D-erythro-Sphingosine-C20-1-phosphate in blood is a potential biomarker for early detection of cancer or vascular diseases. | | Biological Activity | Sphingosine-1-phosphate (S1P) is an important cellular metabolite and signaling lipid in animal cells. It aids in various physiological and cellular processes such as atherosclerosis, inflammation, immunity, tumorigenesis, and cell proliferation. S1P plays a vital role in mammalian brain and cardiac development. S1P d20:1 serves as a partial agonist at the S1P receptor 2 (S1P2). It has an ability to inhibit S1P d18:1‐mediated cyclooxygenase 2(COX2) induction. |
| | D-erythro-sphingosine-1-phosphate (C20 base) Preparation Products And Raw materials |
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