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| | 3,3',4,4'-Biphenyltetramine tetrahydrochloride Basic information |
| Product Name: | 3,3',4,4'-Biphenyltetramine tetrahydrochloride | | Synonyms: | DAB (DiaMinobenzidine) tetrahydrochloride;3,3-DiaMonobenzidine tetrahydrchloride;[1,1'-Biphenyl]-3,3',4,4'-tetraMine, hydrochloride (1:4);3,3′-Diaminobenzidine Peroxidase Substrate;SIGMAFAST? DAB with Metal Enhancer;DAB, 50X;DAB LIQUID SUBSTRATE DROPPER SYSTEM,*TRU -MEASURE CH;3,3',4,4'-BIPHENYLTETRAMINE 4HCL | | CAS: | 7411-49-6 | | MF: | C12H18Cl4N4 | | MW: | 360.11 | | EINECS: | 231-018-9 | | Product Categories: | Industrial/Fine Chemicals;Blotting/Histochemistry SubstratesWestern Blotting;Blotting/Histochemistry SubstratesImmunohistochemistry;Liquid Substrate SystemsImmunohistochemistry;Alkaline Phosphatase;Alphabetical ListingSubstrates, Buffers&Blockers;Detection Substrates;Enzyme Substrates;Liquid Substrate Systems;Peroxidase;Substrates for Peroxidase;Enzyme substrates;Liquid Substrate SystemsEnzyme Substrates;Peroxidase Substrates;Substrates by Enzyme;amino | | Mol File: | 7411-49-6.mol |  |
| | 3,3',4,4'-Biphenyltetramine tetrahydrochloride Chemical Properties |
| Melting point | 300°C | | storage temp. | 2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) | | form | tablets | | color | Crystals | | PH | pH(25℃) : 7.4～7.8 | | Water Solubility | Soluble | | Sensitive | Moisture Sensitive/Air Sensitive | | BRN | 1212988 | | Stability: | Hygroscopic | | InChI | InChI=1S/C12H14N4.4ClH/c13-9-3-1-7(5-11(9)15)8-2-4-10(14)12(16)6-8;;;;/h1-6H,13-16H2;4*1H | | InChIKey | KJDSORYAHBAGPP-UHFFFAOYSA-N | | SMILES | C1(C2=CC=C(N)C(N)=C2)=CC=C(N)C(N)=C1.[H]Cl.[H]Cl.[H]Cl.[H]Cl | | CAS DataBase Reference | 7411-49-6(CAS DataBase Reference) | | EPA Substance Registry System | [1,1'-Biphenyl]-3,3',4,4'-tetramine, tetrahydrochloride (7411-49-6) |
| | 3,3',4,4'-Biphenyltetramine tetrahydrochloride Usage And Synthesis |
| Chemical Properties | Grey Solid | | Uses | A substrate for peroxidase, and a reagent for the spectrophotometric determination of selenium | | Uses | 3,3′-Diaminobenzidine (DAB) Enhanced Liquid Substrate System tetrahydrochloride has been used:
- in the detection of hydrogen peroxide in rice leaves
- as a substrate for rabbit peroxidase in immunohistochemistry of mice brain sections
- in immunocytochemistry of muscle-derived stem cells (MDSCs)
| | Uses | 3,3′-Diaminobenzidine tetrahydrochloride has been used for immunohistochemistry. | | General Description | 3,3′-Diaminobenzidine (DAB) is a chromogenic substrate for peroxidase enzyme. It is converted to an insoluble precipitate after oxidation by peroxidase. | | Biochem/physiol Actions | 3,3′-Diaminobenzidine (DAB) is a chromogenic substrate for peroxidase enzyme. It is converted to an insoluble precipitate after oxidation by peroxidase. This feature is exploited for visualization in histochemical (HC) and immunohistochemical (IHC) staining. | | Safety Profile | Suspected carcinogen withexperimental neoplastigenic and tumorigenic data. Poisonby intraperitoneal route. When heated to decomposition itemits very toxic fumes of HCl and NOx. | | Purification Methods | Dissolve the salt in water and precipitate it by adding conc HCl, then drying it over solid NaOH. [Beilstein 13 IV 530.] |
| | 3,3',4,4'-Biphenyltetramine tetrahydrochloride Preparation Products And Raw materials |
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