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| Product Name: | PAX7B | | Synonyms: | ANTI-PAX7 antibody produced in mouse;PAX7;HUP1;PAX7B | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![PAX7B Structure]() |
| | PAX7B Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution | | biological source | mouse |
| Storage Class | 10 - Combustible liquids |
| | PAX7B Usage And Synthesis |
| Uses | This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) | | Biological Activity | Paired box 7 (PAX7) in muscle-derived stem cells, plays an essential role in myogenic satellite cell specification, by inhibiting alternate developmental programs. Variation in the gene expression is associated with melanoma, neuroblastoma, rhabdomyosarcoma. PAX7 and PAX3 is also implicated in skeletal muscle formation and regeneration. |
| | PAX7B Preparation Products And Raw materials |
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