1-Chloro-4-(2-chloroethoxy)benzene manufacturers
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| | 1-Chloro-4-(2-chloroethoxy)benzene Basic information |
| Product Name: | 1-Chloro-4-(2-chloroethoxy)benzene | | Synonyms: | 2-(4-CHLOROPHENOXY)ETHYL CHLORIDE;1-CHLORO-4-(2-CHLOROETHOXY)BENZENE;4-(2-Chloroethoxy)-Chloro-Benzene;1-Chloro-2-(4-chlorophenoxy)ethane;1-Chloro-4-(chloroethoxy)-benzene;Benzene, 1-chloro-4-(2-chloroethoxy)- | | CAS: | 13001-28-0 | | MF: | C8H8Cl2O | | MW: | 191.05 | | EINECS: | 235-833-0 | | Product Categories: | | | Mol File: | 13001-28-0.mol |  |
| | 1-Chloro-4-(2-chloroethoxy)benzene Chemical Properties |
| | 1-Chloro-4-(2-chloroethoxy)benzene Usage And Synthesis |
| Synthesis | Example P1: Synthesis of 4-chloro-(2-chloroethoxy)-benzene
1. 1 g of tributylamine was added to the reactor as a catalyst, followed by the sequential addition of 26.4 g of 4-chlorophenol and 18.7 g of ethylene carbonate.
2. The reaction mixture was slowly heated to 150 °C and the reaction was maintained at this temperature for about 3 hours until the release of carbon dioxide gas ceased.
3. Upon completion of the reaction, the mixture was cooled to 85 °C and 1 g of dimethylformamide was added as a solvent.
4. 24 g of phosgene was passed into the reaction mixture in the form of a bulb at 85 °C.
5. The reaction temperature was maintained at 85 °C for 8 hours, after which the temperature was reduced to 60 °C. The reaction temperature was reduced to 60 °C.
6. 100 ml of water was added to quench the excess phosgene, followed by neutralization of the reaction mixture with 10.5 g of 25% aqueous sodium hydroxide.
7. The organic layer was separated and purified by reduced pressure distillation (150°-152 °C/40 mb) to give 36.0 g (93% yield) of the target product 4-chloro-(2-chloroethoxy)-benzene. | | References | [1] Patent: US4959501, 1990, A
[2] Patent: US4806528, 1989, A |
| | 1-Chloro-4-(2-chloroethoxy)benzene Preparation Products And Raw materials |
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