- Entecavir Impurity
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- $1.00 / 1g
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2019-12-24
- CAS:1333204-94-6
- Min. Order: 1g
- Purity: 99.99%
- Supply Ability: 200kg
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| | Entecavir Impurity Basic information |
| Product Name: | Entecavir Impurity | | Synonyms: | Entecavir Hydrate IMP;(1R,3S,4S)-ent-Entecavir;6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-, rel-;Entecavir (R,S,S)-Isomer;rel-2-Amino-9-((1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-3,9-dihydro-6H-purin-6-one;Entecavir Impurity | | CAS: | 1333204-94-6 | | MF: | C12H15N5O3 | | MW: | 277.28 | | EINECS: | | | Product Categories: | | | Mol File: | 1333204-94-6.mol |  |
| | Entecavir Impurity Chemical Properties |
| Boiling point | 661.4±65.0 °C(Predicted) | | density | 1.81±0.1 g/cm3(Predicted) | | pka | 14.22±0.60(Predicted) |
| | Entecavir Impurity Usage And Synthesis |
| Uses | (1R,3S,4S)-Entecavir is an impurity of Entecavir (E558900). | | Definition | ChEBI: Entecavir (anhydrous) is guanine substituted at the 9 position by a 4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl group. A synthetic analogue of 2'-deoxyguanosine, it is a nucleoside reverse transcriptase inhibitor with selective antiviral activity against hepatitis B virus. Entecavir is phosphorylated intracellularly to the active triphosphate form, which competes with deoxyguanosine triphosphate, the natural substrate of hepatitis B virus reverse transcriptase, inhibiting every stage of the enzyme's activity, although it has no activity against HIV. It is used for the treatment of chronic hepatitis B. It has a role as an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor and an antiviral drug. It is a member of 2-aminopurines, an oxopurine, a primary alcohol and a secondary alcohol. |
| | Entecavir Impurity Preparation Products And Raw materials |
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