TFMB-(R)-2-HG manufacturers
- TFMB-(R)-2-HG
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- $70.00
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2026-06-02
- CAS:1445700-01-5
- Purity: 99.10%
- Supply Ability: 10g
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| | TFMB-(R)-2-HG Basic information |
| Product Name: | TFMB-(R)-2-HG | | Synonyms: | TFMB-(R)-2-HG;2-Furancarboxylic acid, tetrahydro-5-oxo-, [3-(trifluoromethyl)phenyl]methyl ester, (2R)-;3-(Trifluoromethyl)benzyl (R)-5-oxotetrahydrofuran-2-carboxylate;inhibit,TFMB (R) 2 HG,Inhibitor,TFMB(R)2HG;TFMB-(R)-2-H;TFMB-(R)-2-HG, 10 mM in DMSO | | CAS: | 1445700-01-5 | | MF: | C13H11F3O4 | | MW: | 288.22 | | EINECS: | | | Product Categories: | | | Mol File: | 1445700-01-5.mol |  |
| | TFMB-(R)-2-HG Chemical Properties |
| Boiling point | 376.3±42.0 °C(Predicted) | | density | 1.385±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 30 mg/ml | | form | A crystalline solid | | color | White to off-white |
| | TFMB-(R)-2-HG Usage And Synthesis |
| Uses | TFMB-(R)-2-HG, a cell membrane-permeable version of (R)-2-HG, is a carcinogenic factor in Acute myeloid leukemia (AML).
TFMB-(R)-2-HG impairs SCF ER-Hoxb8 cells differentiation in response to estrogen withdrawal[1]. | | References | [1] Losman JA, et al. (R)-2-hydroxyglutarate is sufficient to promote leukemogenesis and its effects are reversible. Science. 2013 Mar 29;339(6127):1621-5. DOI:10.1126/science.1231677 |
| | TFMB-(R)-2-HG Preparation Products And Raw materials |
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