| Company Name: |
Hangzhou Peptidego Biotech Co.,Ltd.
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| Tel: |
0571-87213919 |
| Email: |
Eric@peptidego.com |
| Products Intro: |
Product Name:Argifin
CAS:243975-37-3
Purity:95% or 98% HPLC Package:1mg；5mg；10mg；50mg；100mg,1g or according to customer's detail requirement.
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| Company Name: |
Beijing Jin Ming Biotechnology Co., Ltd.
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| Tel: |
010-60605840 15801484223; |
| Email: |
psaitong@jm-bio.com |
| Products Intro: |
Product Name:Argifin
CAS:243975-37-3
Purity:95% Package:100mg;250mg;500mg
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| Company Name: |
Bide Pharmatech Ltd.
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| Tel: |
400-1647117 13681763483 |
| Email: |
product02@bidepharm.com |
| Products Intro: |
Product Name:(2R,5S,8S,11S,15S)-8-Benzyl-2,7-dimethyl-5-(3-(3-(methylcarbamoyl)guanidino)propyl)-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentaazacycloheptadecane-11,15-dicarboxylic acid
CAS:243975-37-3
Purity:98% Package:1mg;5mg;10mg;25mg;50mg Remarks:BD01314977
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| Company Name: |
Xi'an Qiyue Biotechnology Co., Ltd.
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| Tel: |
400-400-6966-012-012 17778955912 |
| Email: |
2957605606@qq.com |
| Products Intro: |
Product Name:Argifin
CAS:243975-37-3
Package:5mg
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| | Argifin Basic information |
| Product Name: | Argifin | | Synonyms: | Cyclo[D-alanyl-N5-[imino[[(methylamino)carbonyl]amino]methyl]-L-ornithyl-N-methyl-L-phenylalanyl-L-b-aspartyl-L-b-aspartyl];argifin;Cyclo[D-alanyl-N5-[imino[[(methylamino)carbonyl]amino]methyl]-L-ornithyl-N-methyl-L-phenylalanyl-L-β-aspartyl-L-β-aspartyl];(2R,5S,8S,11S,15S)-8-Benzyl-2,7-dimethyl-5-(3-(3-(methylcarbamoyl)guanidino)propyl)-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentaazacycloheptadecane-11,15-dicarboxylic acid | | CAS: | 243975-37-3 | | MF: | C29H41N9O10 | | MW: | 675.69014 | | EINECS: | | | Product Categories: | | | Mol File: | 243975-37-3.mol |  |
| | Argifin Chemical Properties |
| density | 1.49±0.1 g/cm3(Predicted) | | form | Solid | | pka | 3.01±0.70(Predicted) | | color | White to off-white | | Sequence | Cyclo({d-Ala}-{N5-[imino[[(methylamino)carbonyl]amino]methyl]-L-ornithyl}-{Phe(Me)}-{Bas}-{Bas}) |
| | Argifin Usage And Synthesis |
| Uses | Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively[1]. | | in vivo | Argifin has the ability to inhibit L. cuprina molting[1].
| | References | [1] Hirose T, et al. Recent development of two chitinase inhibitors, Argifin and Argadin, produced by soil microorganisms. Proc Jpn Acad Ser B Phys Biol Sci. 2010;86(2):85-102. DOI:10.2183/pjab.86.85 |
| | Argifin Preparation Products And Raw materials |
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