- (±)-Naringenin
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- $29.00 / 1mL
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2026-04-14
- CAS:67604-48-2
- Min. Order:
- Purity: 98.73%
- Supply Ability: 10g
- Naringenin
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- $172.00 / 1KG
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2023-04-04
- CAS:67604-48-2
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 50kg
- Naringenin
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- $0.00 / 1g
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2022-05-13
- CAS:67604-48-2
- Min. Order: 10g
- Purity: 99.0%
- Supply Ability: 10tons
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| | NARINGENIN Basic information |
| Product Name: | NARINGENIN | | Synonyms: | (+/-)-2,3-DIHYDRO-5,7-DIHYDROXY-2-(4-HYDROXYPHENYL)-4H-1-BENZOPYRAN-4-ONE;TIMTEC-BB SBB006461;5,7,4'-TRIHYDROXYFLAVANONE;5,7-DIHYDROXY-2-(4-HYDROXYPHENYL)CHROMAN-4-ONE;4',5,7-Trihydroxyflavanone,97%;4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-;4μ,5,7-Trihydroxyflavanone, (±)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;(±)-Naringenin, 4μ,5,7-Trihydroxyflavanone, (±)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one | | CAS: | 67604-48-2 | | MF: | C15H12O5 | | MW: | 272.25 | | EINECS: | 266-769-1 | | Product Categories: | and Flavanols;Benzopyrans;Bioactive Small Molecules;Building Blocks;Cell Biology;Chemical Synthesis;Citrus aurantium (Seville orange);Flavonols;Heterocyclic Building Blocks;N;Nutrition Research;Phytochemicals by Chemical Classification;Phytochemicals by Plant (Food/Spice/Herb);Aromatics;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Biochemistry;Flavonoids | | Mol File: | 67604-48-2.mol |  |
| | NARINGENIN Chemical Properties |
| Melting point | 247-250 °C (lit.) | | Boiling point | 577.5±50.0 °C(Predicted) | | density | 1.485 | | storage temp. | 2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 7.52±0.40(Predicted) | | form | Solid | | color | Pale Yellow to Pale Brown | | biological source | Citrus paradisi Macf. | | Water Solubility | Soluble in ethanol (50 mg/ml), DMSO, methanol, and ammonium hydroxide (50 mg/ml). Insoluble in water (almost) | | Merck | 14,6424 | | InChI | InChI=1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2 | | InChIKey | FTVWIRXFELQLPI-UHFFFAOYSA-N | | SMILES | C1(C2=CC=C(O)C=C2)OC2=CC(O)=CC(O)=C2C(=O)C1 | | CAS DataBase Reference | 67604-48-2(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | RIDADR | 3077 | | WGK Germany | 3 | | RTECS | DJ2981530 | | HS Code | 29329990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral |
| | NARINGENIN Usage And Synthesis |
| Chemical Properties | Pale Yellow to Pale Brown Solid | | Uses | A PI 3-kinase inhibitor. | | Uses | The aglucon of Naringin. Inhibitory mechanism of Naringenin against carcinogenic acrylamide formation and nonenzymic browning in Maillard model reactions. | | Definition | ChEBI: Naringenin is a trihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5, 6 and 4'. It is a trihydroxyflavanone and a member of 4'-hydroxyflavanones. | | General Description | Naringenin is a bioactive flavonoid found in citrus and grapefruit. | | in vivo | (±)-Naringenin (50 mg/kg, orally, once a day for ten days) significantly reduces the severity of DSS-induced colitis in mice and downregulats pro-inflammatory mediators (iNOS, ICAM-1, MCP-1, Cox2, TNF-α, and IL-6 mRNA) in the colonic mucosa[2]. | Animal Model: | C57BL/6[2] | | Dosage: | 50 mg/kg | | Administration: | Oral; daily; 10 days | | Result: | Reduced the severity of DSS-induced colitis in mice, downregulated pro-inflammatory mediators (iNOS, ICAM-1, MCP-1, Cox2, TNF-α, and IL-6 mRNA) in the colonic mucosa, inhibited the increase in TLR4 mRNA and protein levels, and reduced the phosphorylated NF-κB p65 protein level. |
| | IC 50 | NF-κB; Caspase 9 |
| | NARINGENIN Preparation Products And Raw materials |
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