BAY-1895344 (hydrochloride)

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BAY-1895344 (hydrochloride) Suppliers list
Company Name: MedChemexpress LLC  
Tel: 021-58955995
Email: sales@medchemexpress.cn
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Tel: 15026964105
Email: 2881489226@qq.com
Company Name: BOC Sciences  
Tel: 16314854226; +8616314854226
Email: inquiry@bocsci.com
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
Tel: 18818260767
Email: sales@chemegen.com

BAY-1895344 (hydrochloride) manufacturers
BAY-1895344 (hydrochloride) Basic information
Product Name:BAY-1895344 (hydrochloride)
Synonyms:BAY-1895344 (hydrochloride);Elimusertib hydrochloride(1876467-74-1 free base);Elimusertib hydrochloride(1876467 74 1 free base),Elimusertib hydrochloride(1876467741 free base)
CAS:
MF:C??H??ClN?O
MW:0
EINECS:
Product Categories:
Mol File:Mol File
BAY-1895344 (hydrochloride) Structure
BAY-1895344 (hydrochloride) Chemical Properties
solubility DMSO: 30 mg/ml
Ethanol: 30 mg/ml
Water: 30 mg/ml
Safety Information
MSDS Information
BAY-1895344 (hydrochloride) Usage And Synthesis
DescriptionBAY-1895344 is an inhibitor of ataxia-telangiectasia and Rad3-related protein (ATR) kinase that inhibits proliferation in a panel of human tumor cell lines (mean IC50 = 78 nM). It halts tumor growth in ovarian and colorectal mouse xenograft models and induces complete tumor remission in mantle cell lymphoma mouse xenograft models. BAY-1895344 also exhibits synergistic anti-tumor activity with radium-223 in a mouse xenograft model of castration-resistant prostate cancer bone metastases.
References[1] A. WENGNER. Abstract 836: ATR inhibitor BAY 1895344 shows potent anti-tumor efficacy in monotherapy and strong combination potential with the targeted alpha therapy Radium-223 dichloride in preclinical tumor models[J]. Cancer research, 2017, 77 1: 836-836. DOI: 10.1158/1538-7445.am2017-836
BAY-1895344 (hydrochloride) Preparation Products And Raw materials
Tag:BAY-1895344 (hydrochloride) Related Product Information
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