- 6-Hydroxyflavone
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- $29.00 / 100mg
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2026-01-26
- CAS:6665-83-4
- Min. Order:
- Purity: 99.93%
- Supply Ability: 10g
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| | 6-HYDROXYFLAVONE Basic information |
| | 6-HYDROXYFLAVONE Chemical Properties |
| Melting point | 234-236 °C (lit.) | | Boiling point | 320.83°C (rough estimate) | | density | 1.2653 (rough estimate) | | refractive index | 1.5740 (estimate) | | form | powder to crystal | | pka | 8.98±0.40(Predicted) | | color | Light yellow to Yellow to Green | | BRN | 15827 | | InChI | 1S/C15H10O3/c16-11-6-7-14-12(8-11)13(17)9-15(18-14)10-4-2-1-3-5-10/h1-9,16H | | InChIKey | GPZYYYGYCRFPBU-UHFFFAOYSA-N | | SMILES | Oc1ccc2OC(=CC(=O)c2c1)c3ccccc3 | | LogP | 4.445 (est) | | CAS DataBase Reference | 6665-83-4(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39 | | WGK Germany | 3 | | Hazard Note | Irritant | | HS Code | 2932.99.7000 | | Storage Class | 11 - Combustible Solids |
| | 6-HYDROXYFLAVONE Usage And Synthesis |
| Chemical Properties | light yellow crystals | | Uses | anxiolytic | | Definition | ChEBI: 6-Hydroxyflavone is a hydroxyflavonoid. | | Synthesis Reference(s) | Tetrahedron Letters, 27, p. 2751, 1986 DOI: 10.1016/S0040-4039(00)84634-1 | | in vivo | 6-Hydroxyflavone (6-100 mg/kg; Oral administration; Single dose; 45 minutes before test) has anti-anxiety effect in mouse model[4].
6-Hydroxyflavone (25-50 mg/kg; Intraperitoneal injection; 15 days) shows protective effect in Cisplatin (HY-17394) -induced nephrotoxicity rat model[5]. | Animal Model: | Male ICR mice (20-36 g)[4] | | Dosage: | 6, 12, 25, 50 and 100 mg/kg | | Administration: | Oral administration (p.o.); Single dose; 45 minutes before test | | Result: | Showed anti-anxiety effects on behavioral tests.
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| Animal Model: | Cisplatin (HY-17394) treated male Sprague-Dawley rats (200-250 g)[5] | | Dosage: | 25 and 50 mg/kg | | Administration: | Intraperitoneal injection (i.p.); 15 days | | Result: | Significantly attenuated the Cisplatin associated detrimental changes in the body weight, and serum levels of creatinine and urea at both 25 mg/kg and 50 mg/kg.
Preserved the renal histoarchitecture from the toxicological influence of Cisplatin.
Reduced the Cisplatin-induced lipid peroxidation and corrected the renal antioxidant status.
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| | 6-HYDROXYFLAVONE Preparation Products And Raw materials |
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Tag:6-HYDROXYFLAVONE(6665-83-4)
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