DNQX disodiumsalt manufacturers
- DNQX disodium salt
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- $56.00 / 1mg
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2026-01-05
- CAS:1312992-24-7
- Min. Order:
- Purity: 100.00%
- Supply Ability: 10g
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| | DNQX disodiumsalt Basic information |
| Product Name: | DNQX disodiumsalt | | Synonyms: | 3-bis(olate);3-dione disodium salt;sodium 6;SODIUM 6;7-DINITROQUINOXALINE-2;3-BIS(OLATE);6;7-DINITROQUINOXALINE-2;3-DIONE DISODIUM SALT;DNQX Disodium;quinoxaline,inhibit,Inhibitor,iGluR,competitive,DNQX disodium salt,non-NMDA,Ionotropic glutamate receptors,nucleus,selective,FG 9041 disodium,thalamic,reticular;DNQX disodium salt, 10 mM in DMSO | | CAS: | 1312992-24-7 | | MF: | C8H5N4NaO6 | | MW: | 276.14 | | EINECS: | | | Product Categories: | | | Mol File: | 1312992-24-7.mol |  |
| | DNQX disodiumsalt Chemical Properties |
| storage temp. | Store at -20°C | | solubility | 5mg/mL in DMSO, 12mg/mL in DMF | | form | solid | | color | Brown | | Water Solubility | Soluble in water (100mM) |
| | DNQX disodiumsalt Usage And Synthesis |
| Description | DNQX Disodium is a water-soluble form of selective non-NMDA receptor antagonist DNQX. | | Uses | DNQX (FG 9041) disodium salt, a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively)[1]. | | in vivo | DNQX (FG 9041), a specific AMPA receptor antagonist, given as either a 5 mg/kg or 10 mg/kg intraperitoneal dose or into the lateral cerebral ventricle (5 μl of 0.5 mg/ml) significantly diminishes phencyclidine (PCP) (40 mg/kg) and ketamine (80, 100, 120 mg/kg) hsp70 induction in the posterior cingulate and retrosplenial cortex[3]. | | storage | Room temperature (desiccate) | | References | [1] Honoré T, et al. Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists. Science. 1988;241(4866):701-703. DOI:10.1126/science.2899909
[2] Lee SH, et al. Selective excitatory actions of DNQX and CNQX in rat thalamic neurons. J Neurophysiol. 2010;103(4):1728-1734. DOI:10.1152/jn.00540.2009
[3] Sharp JW, et al. DNQX inhibits phencyclidine (PCP) and ketamine induction of the hsp70 heat shock gene in the rat cingulate and retrosplenial cortex. Brain Res. 1995;687(1-2):114-124. DOI:10.1016/0006-8993(95)00477-8 |
| | DNQX disodiumsalt Preparation Products And Raw materials |
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