3-(1H-benzo[d]imidazol-2-yl)quinoline-2,4-diol

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Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

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3-(1H-benzo[d]imidazol-2-yl)quinoline-2,4-diol Basic information
Product Name:3-(1H-benzo[d]imidazol-2-yl)quinoline-2,4-diol
Synonyms:3-(1H-benzo[d]imidazol-2-yl)quinoline-2,4-diol;2(1H)-Quinolinone, 3-(1H-benzimidazol-2-yl)-4-hydroxy-;FGF/PDGF/VEGF RTK Inhibitor
CAS:144335-37-5
MF:C16H11N3O2
MW:277.28
EINECS:
Product Categories:
Mol File:144335-37-5.mol
3-(1H-benzo[d]imidazol-2-yl)quinoline-2,4-diol Structure
3-(1H-benzo[d]imidazol-2-yl)quinoline-2,4-diol Chemical Properties
density 1.499±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: 5mg/mL
pka4.50±1.00(Predicted)
form solid
color off-white
InChI1S/C16H11N3O2/c20-14-9-5-1-2-6-10(9)19-16(21)13(14)15-17-11-7-3-4-8-12(11)18-15/h1-8H,(H,17,18)(H2,19,20,21)
InChIKeyYXCWBNCDJZEBKY-UHFFFAOYSA-N
SMILES[nH]1c2c(nc1c3c(nc4c(c3O)cccc4)O)cccc2
Safety Information
WGK Germany WGK 2
Storage Class11 - Combustible Solids
MSDS Information
3-(1H-benzo[d]imidazol-2-yl)quinoline-2,4-diol Usage And Synthesis
DescriptionFGF/PDGF/VEGF RTK Inhibitor is a potent, reversible, atp-competitive inhibitor against pdgfrβ, fgfr-1, and vegfr-2 (ic50 = 20, 90, and 240 nm, respectively) and effectively suppresses vegf-stimulated proliferation of hmvecs (ec50 = 420 nm).
3-(1H-benzo[d]imidazol-2-yl)quinoline-2,4-diol Preparation Products And Raw materials
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