5-(5-bromofuran-2-yl)-3-pyridin-2-yl-1,2,4-oxadiazole

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5-(5-bromofuran-2-yl)-3-pyridin-2-yl-1,2,4-oxadiazole Basic information
Product Name:5-(5-bromofuran-2-yl)-3-pyridin-2-yl-1,2,4-oxadiazole
Synonyms:5-(5-bromofuran-2-yl)-3-pyridin-2-yl-1,2,4-oxadiazole;Pyridine, 2-[5-(5-bromo-2-furanyl)-1,2,4-oxadiazol-3-yl]-;Luciferase-IN-3
CAS:690987-97-4
MF:C11H6BrN3O2
MW:292.09
EINECS:
Product Categories:
Mol File:690987-97-4.mol
5-(5-bromofuran-2-yl)-3-pyridin-2-yl-1,2,4-oxadiazole Structure
5-(5-bromofuran-2-yl)-3-pyridin-2-yl-1,2,4-oxadiazole Chemical Properties
Boiling point 431.9±55.0 °C(Predicted)
density 1.609±0.06 g/cm3(Predicted)
form Solid
pka-2.16±0.19(Predicted)
Safety Information
MSDS Information
5-(5-bromofuran-2-yl)-3-pyridin-2-yl-1,2,4-oxadiazole Usage And Synthesis
UsesLuciferase-IN-3 (compound 5h) is an inhibitor of ATP-dependent luciferase (Firefly luciferase), the major light-emitting enzyme in fireflies and kowtow bugs. Firefly luciferase-IN-2 inhibits P. pyralis luciferase with an IC50 of 3.2 μM, while the inhibitory potency against R. reniformis is not significant[1].
References[1] Auld DS, et al. Characterization of chemical libraries for luciferase inhibitory activity. J Med Chem. 2008 Apr 24;51(8):2372-86. DOI:10.1021/jm701302v
5-(5-bromofuran-2-yl)-3-pyridin-2-yl-1,2,4-oxadiazole Preparation Products And Raw materials
Tag:5-(5-bromofuran-2-yl)-3-pyridin-2-yl-1,2,4-oxadiazole(690987-97-4) Related Product Information
Fluorescein 5-isothiocyanate Nile Red BACLIGHT(TM) GREEN BACTERIAL STAIN Fluorescein isothiocyanate-dextran Dihydroethidium 5(6)-(N-Succinimidyloxycarbonyl)-3',6',O,O'-diacetylfluorescein