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Alfa Chemistry |
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| | (16(17)-DiHDPA Basic information |
| Product Name: | (16(17)-DiHDPA | | Synonyms: | (16(17)-DiHDPA;(±)16(17)-DiHDPA MaxSpec? Standard;16,17-dihydroxy-4(Z),7(Z),10(Z),13(Z),19(Z)-docosapentaenoic acid;4,7,10,13,19-Docosapentaenoic acid, 16,17-dihydroxy-, (4Z,7Z,10Z,13Z,19Z)-;(±)16(17)-DiHDPA;16,17-Dihydroxy-4(Z),7(Z),10(Z),13(Z),19(Z)-DPA | | CAS: | 1345275-27-5 | | MF: | C22H34O4 | | MW: | 362.5 | | EINECS: | | | Product Categories: | | | Mol File: | 1345275-27-5.mol |  |
| | (16(17)-DiHDPA Chemical Properties |
| Boiling point | 537.8±50.0 °C(Predicted) | | density | 1.035±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.25 mg/ml | | pka | 4.58±0.10(Predicted) |
| | (16(17)-DiHDPA Usage And Synthesis |
| Description | (±)16(17)-DiHDPA is produced from cytochrome P450 epoxygenase action on docosahexaenoic acid (DHA; ). It has been shown to inhibit VEGF-induced angiogenesis and reduce cancer cell metastasis in mice.1 | | Uses | (±)16(17)-DiHDPA is a epoxygenase metabolite of docosahexaenoic acid (HY-B2167). (±)16(17)-DiHDPA inhibits platelet aggregation at concentrations below those affecting thromboxane synthesis[1][2]. | | Definition | ChEBI: 16,17-DiHDPE is a very long-chain fatty acid. | | References | 1. Zhang, G., Panigrahy, D., Mahakian, L.M., et al. Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis Proc. Natl. Acad. Sci. USA 110(16),6530-6535(2013). |
| | (16(17)-DiHDPA Preparation Products And Raw materials |
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