| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:ABI-1968
CAS:1626364-18-8
Purity:98.00% Package:1mg;5mg
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:ABI-1968
CAS:1626364-18-8
Purity:98.54% Package:1mg/RMB 7000;5mg/RMB 12800
|
ABI-1968 manufacturers
- ABI-1968
-
- $970.00 / 1mg
-
2024-11-12
- CAS:1626364-18-8
- Min. Order:
- Purity: 98.54%
- Supply Ability: 10g
|
| | ABI-1968 Basic information |
| Product Name: | ABI-1968 | | Synonyms: | ABI-1968;Phosphonic acid, P-[[2-(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)ethoxy]methyl]-, 2-(octadecyloxy)ethyl phenylmethyl ester | | CAS: | 1626364-18-8 | | MF: | C35H58N5O6P | | MW: | 675.84 | | EINECS: | | | Product Categories: | | | Mol File: | 1626364-18-8.mol |  |
| | ABI-1968 Chemical Properties |
| Boiling point | 804.2±75.0 °C(Predicted) | | density | 1.18±0.1 g/cm3(Predicted) | | pka | 3.39±0.20(Predicted) |
| | ABI-1968 Usage And Synthesis |
| Uses | ODE-Bn-PMEG is an antiviral compound with strong inhibitory activity against HPV-11, -16, and -18. ODE-Bn-PMEG effectively reduced transient amplification of viral DNA in transfected cells at concentrations well below its cytotoxic levels. ODE-Bn-PMEG showed increased uptake in human foreskin fibroblasts and was able to be efficiently converted to the active antiviral metabolite PMEG diphosphate in vitro. The P-chiral enantiomer of ODE-Bn-PMEG showed comparable antiviral activity, indicating its potential application against multiple HPV types. ODE-Bn-PMEG is a promising candidate for local inhibition of HPV-16, HPV-18, and other high-risk types[1]. | | References | [1] Synthesis and Antiviral Evaluation of Octadecyloxyethyl Benzyl 9-[(2-Phosphonomethoxy)ethyl]guanine (ODE-Bn-PMEG), a Potent Inhibitor of Transient HPV DNA Amplification DOI:10.1021/acs.jmedchem.6b00659 |
| | ABI-1968 Preparation Products And Raw materials |
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