- 2-Amino-5-fluoropyridine
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- $0.00 / 100gm
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2026-04-27
- CAS:21717-96-4
- Min. Order: 100gm
- Purity: 99%min
- Supply Ability: 100kgs
- 2-Amino-5-fluoropyridine
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- $6.00 / 1KG
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2025-09-25
- CAS:21717-96-4
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| | 2-Amino-5-fluoropyridine Basic information |
| | 2-Amino-5-fluoropyridine Chemical Properties |
| Melting point | 93-97 °C (lit.) | | Boiling point | 125 °C | | density | 1.257±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | soluble in Methanol | | form | Powder | | pka | 4.62±0.13(Predicted) | | color | White to orange | | BRN | 385938 | | InChI | InChI=1S/C5H5FN2/c6-4-1-2-5(7)8-3-4/h1-3H,(H2,7,8) | | InChIKey | YJTXQLYMECWULH-UHFFFAOYSA-N | | SMILES | C1(N)=NC=C(F)C=C1 | | CAS DataBase Reference | 21717-96-4(CAS DataBase Reference) |
| Hazard Codes | Xi,C | | Risk Statements | 36/37/38-34 | | Safety Statements | 26-36-45-36/37/39-27 | | RIDADR | UN2811 | | WGK Germany | 3 | | Hazard Note | Irritant | | HazardClass | 6.1 | | PackingGroup | II | | HS Code | 29333999 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 2-Amino-5-fluoropyridine Usage And Synthesis |
| Chemical Properties | Light yellow Cryst | | Uses | 2-Amino-5-fluoropyridine is used in chemical microarrays to identify ligands that binds pathogenic cells. Acts as a reagent in the preparation of heterocyclic compounds as integrase inhibiting antiviral agents. | | Definition | ChEBI: 2-Amino-5-fluoropyridine is a dihydropyridine. | | Application | 2-Amino-5-fluoropyridine is a versatile fluorinated pyridine building block widely used to prepare peptide deformylase inhibitors such as the antibacterial agent LBM415, as well as herbicides, fungicides, and PET imaging probes; the combined electron-withdrawing fluorine and nucleophilic amino substituents enhance metabolic stability and bioavailability of the resulting active pharmaceutical or agrochemical ingredients. | | Synthesis | 2-Amino-5-fluoropyridine is an important intermediate for the synthesis of LBM415 which is the peptide deformylas inhibitor. Using 2-aminopyridine as raw material and via nitrification, amino acetylation, reduction of nitro, diazolization, Schiemann reaction and hydrolysis of acetyl. | | References | [1] E. S. HAND, D. C. BAKER. “ChemInform Abstract: Syntheses of 2-Chloro- and 2-Amino-5-fluoropyridines and Isolation of a Novel Difluoroboryl Imidate.” ChemInform 21 19 (1990).
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| | 2-Amino-5-fluoropyridine Preparation Products And Raw materials |
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