- 2-BROMOACETAMIDE
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- $10.00 / 1KG
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2026-01-05
- CAS:683-57-8
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 mt
- 2-BROMOACETAMIDE
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- $0.00 / 25kg
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2025-12-01
- CAS:683-57-8
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 10000KGS
- 2-Bromoacetamide
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- $10.70 / 1kg
-
2025-05-26
- CAS:683-57-8
- Min. Order: 10kg
- Purity: 99%
- Supply Ability: 10000kg
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| | 2-BROMOACETAMIDE Basic information |
| | 2-BROMOACETAMIDE Chemical Properties |
| Melting point | 87-91 °C(lit.) | | Boiling point | 271.6±23.0 °C(Predicted) | | density | 1.4243 (rough estimate) | | refractive index | 1.4740 (estimate) | | storage temp. | Inert atmosphere,2-8°C | | solubility | 160g/l | | form | Crystalline Powder | | pka | 14.79±0.40(Predicted) | | color | White | | BRN | 1739073 | | InChI | InChI=1S/C2H4BrNO/c3-1-2(4)5/h1H2,(H2,4,5) | | InChIKey | JUIKUQOUMZUFQT-UHFFFAOYSA-N | | SMILES | C(N)(=O)CBr | | CAS DataBase Reference | 683-57-8(CAS DataBase Reference) |
| Hazard Codes | T,C | | Risk Statements | 25-34-20/21/22 | | Safety Statements | 26-27-36/37/39-45 | | RIDADR | UN 2923 8/PG 2 | | WGK Germany | 3 | | RTECS | AB4587000 | | F | 10 | | Hazard Note | Irritant | | HazardClass | 8 | | PackingGroup | III | | HS Code | 29241990 | | Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials | | Hazard Classifications | Acute Tox. 3 Oral
Eye Dam. 1
Skin Corr. 1B |
| | 2-BROMOACETAMIDE Usage And Synthesis |
| Chemical Properties | Very faintly beige fine crystals | | Uses | 2-Bromoacetamide was used in preparation of (2-carbamoylmethoxy-5-chloro-benzyl)-carbamic acid tert-butyl ester. It was aslo used as precursor to dehydropeptidase I inactivator. | | General Description | Kinetics of reaction of 2-bromoacetamide with a 39 base pair duplex DNA sequence was studied. | | Hazard | A poison by ingestion. Moderately toxic by
skin contact. A severe skin and eye irritant. | | Synthesis | Step 1: To a dichloromethane solution containing the amine (300 mg, 0.71 mmol) and potassium carbonate (290 mg, 2.1 mmol) obtained from Step 1 of Example 51 was slowly added bromoacetyl chloride (71 μL, 0.85 mmol) at room temperature. The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the reaction mixture was washed with 0.1 N NaOH aqueous solution and subsequently dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure and the residue was purified by silica gel column chromatography (eluent: dichloromethane/ethyl acetate, 9:1, v/v) to afford the target product 2-bromoacetamide 281 mg in 73% yield. | | References | [1] Journal of the American Chemical Society, 1939, vol. 61, p. 3386
[2] Patent: US2003/216380, 2003, A1 |
| | 2-BROMOACETAMIDE Preparation Products And Raw materials |
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