| Company Name: |
Sigma-Aldrich |
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
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| | LIPOPOLYSACCHARIDES FROM ESCHERICHIA COLI O111:B4 Basic information |
| | LIPOPOLYSACCHARIDES FROM ESCHERICHIA COLI O111:B4 Chemical Properties |
| storage temp. | 2-8°C | | form | lyophilized powder | | color | yellow to orange | | biological source | Escherichia coli (O111:B4) | | Water Solubility | water: soluble |
| | LIPOPOLYSACCHARIDES FROM ESCHERICHIA COLI O111:B4 Usage And Synthesis |
| Uses | Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs). | | Uses | FITC-Lipopolysaccharides (FITC-LPS) may be used to study processes such as the movement/transport of LPS across tissue barriers such as the colonic epithelium and cellular binding and internalization of lipopolysaccharides with fluorescence-based assay systems. It may be used to evaluate, qualify and quantify lipopolysaccharides (LPS) removal reagents and procedures. FITC-LPS conjugate may be used for the detection of LPA binding proteins and motifs. | | General Description | This product is extracted from E. coli serotype O111:B4 and purified by gel filtration. The source strain is from a private collection. This LPS serotype has been used to stimulate B-cells and induce NOS in human hepatocytes. | | Biochem/physiol Actions | Lipopolysaccharides (LPS) are localized in the outer layer of the membrane and are, in noncapsulated strains, exposed on the cell surface. They contribute to the integrity of the outer membrane, and protect the cell against the action of bile salts and lipophilic antibiotics. |
| | LIPOPOLYSACCHARIDES FROM ESCHERICHIA COLI O111:B4 Preparation Products And Raw materials |
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