Rimegepant sulfate manufacturers
- Rimegepant Sulfate
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- $0.00 / 1g
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2026-04-24
- CAS:1374024-48-2
- Min. Order: 1g
- Purity: 0.99
- Supply Ability: 50kg/Month
- Rimegepant sulfate
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- $5.00/ KG
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2026-04-10
- CAS:1374024-48-2
- Min. Order: 1KG
- Purity: 99% hplc
- Supply Ability: 500TONS
- Rimegepant Sulfate
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- $0.00 / 1kg
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2026-01-04
- CAS:1374024-48-2
- Min. Order: 1kg
- Purity: 99.0%
- Supply Ability: 20 tons
Related articles - Synthesis of Rimegepant Sulfate
- Rimegepant Sulfate is prepared by combining the intermediate compounds Azide and p-nitrocarbamate to form a carbamate intermed....
- Dec 22，2023
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| | Rimegepant sulfate Basic information |
| Product Name: | Rimegepant sulfate | | Synonyms: | [(5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl]4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate;(5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate hemisulfate sesquihydrate;RIMEGEPANT SULFATE;Rimegepant sulfate hydrate【Chemical name：1-Piperidinecarboxylic acid, 4-(2,3-dihydro-2-oxo-1H-imidazo[4,5-b]pyridin-1-yl)-, (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl ester, sulfate, hydrate (2:1:3)】;(5S,6S,9R)-5-amino-6-(2,3difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b] pyridin-9-yl4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)-1-piperidinecarboxylate hemisulfate sesquihydrate;Rimegepant sulfate hydrate;Rimegepant hemisulfate sesquihydrate;Rimegepant 1/2Sulfate 3/2Trihydrate | | CAS: | 1374024-48-2 | | MF: | C28H30F2N6O7S | | MW: | 632.64 | | EINECS: | 822-372-0 | | Product Categories: | API | | Mol File: | 1374024-48-2.mol |  |
| | Rimegepant sulfate Chemical Properties |
| InChIKey | SBWRYPRKGHWPOH-FDZFFRPLNA-N | | SMILES | S(O)(O)(=O)=O.O=C1NC2=NC=CC=C2N1C1CCN(C(=O)O[C@@H]2CC[C@@H](C3C=CC=C(F)C=3F)[C@H](N)C3=CC=CN=C23)CC1 |&1:22,25,34,r| |
| | Rimegepant sulfate Usage And Synthesis |
| Description | Rimegepant sulfate is a small molecule, highly selective calcitonin gene-related peptide antagonist (CGRP) developed by Biohaven Pharmaceutical Holdings, Inc. and approved by the FDA for the acute treatment of migraine. rimegepant and ubrogepant are the only CGRP antagonists with oral bioavailability. Because of the absence of vasoconstrictive properties observed with oral CGRP antagonists, the use of rimegepant is safer and more reliable in patients with contraindications to standard therapy[1]. | | Uses | Rimegepant sulfate is indicated for the acute treatment of migraine and for the preventive treatment of episodic migraine in adults. | | Trade name | Nurtec
| | Mechanism of action | Remegipam sulfate is used for the acute treatment of migraine by antagonizing CGRP receptors, reducing CGRP-induced vasodilation and pain signal transmission.
| | Side effects | Common side effects of Rimegepant sulfate are nausea, which may be severe enough to cause shortness of breath, difficulty breathing; swelling of the face, eyes, mouth, throat, tongue, or lips; rash, measles; and itching. | | Synthesis | Rimegepant sulfate is prepared by the reaction of rimegepant and water.
Step: With sulfuric acid In ethanol at 20 - 70℃; Solvent; Temperature.
| | References | [1] J S. Rimegepant: First Approval.[J]. Drugs, 2020, 80 7: 741-746. DOI:10.1007/s40265-020-01301-3. |
| | Rimegepant sulfate Preparation Products And Raw materials |
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