Adrenomedullin (22-52) (human) (trifluoroacetate salt) manufacturers
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| | Adrenomedullin (22-52) (human) (trifluoroacetate salt) Basic information |
| | Adrenomedullin (22-52) (human) (trifluoroacetate salt) Chemical Properties |
| solubility | Water: 1 mg/ml |
| | Adrenomedullin (22-52) (human) (trifluoroacetate salt) Usage And Synthesis |
| Description | Adrenomedullin (22-52) is a C-terminal fragment of adrenomedullin (1-52) (Item No. 24889).1 In vitro, adrenomedullin (22-52) reduces basal corticosterone production in a mixture of rat adrenocortical and adrenomedulllary cells.2 It also reverses increases in ACTH-stimulated corticosterone production induced by adrenomedullin (1-52). Adrenomedulin (22-52) (0.5 and 5 μg/kg/min) has no effect on basal regional cerebral blood flow but reverses increases in regional cerebral blood flow induced by rat adrenomedullin in rats.3 Unlike adrenomedullin (1-52), adrenomedullin (22-52) has no effect on mesenteric arterial perfusion pressure in cats.1WARNING This product is not for human or veterinary use. | | References | [1] Q TIAN. Vasodilator effect of human adrenomedullin(13-52) on hypertensive rats.[J]. Canadian journal of physiology and pharmacology, 1995, 73 7: 1065-1069. DOI: 10.1139/y95-151 [2] AGNIESZKA ZIOLKOWSKA. Effects of adrenomedullin and its fragment 22-52 on basal and ACTH-stimulated secretion of cultured rat adrenocortical cells.[J]. International journal of molecular medicine, 2003, 11 5: 613-615.
[3] A DOGAN. Intravenous infusion of adrenomedullin and increase in regional cerebral blood flow and prevention of ischemic brain injury after middle cerebral artery occlusion in rats.[J]. Journal of Cerebral Blood Flow and Metabolism, 1997, 17 1: 19-25. DOI: 10.1097/00004647-199701000-00004 |
| | Adrenomedullin (22-52) (human) (trifluoroacetate salt) Preparation Products And Raw materials |
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