- Benzobarbital
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- $10.00 / 1KG
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2026-01-30
- CAS:744-80-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 mt
- Benzobarbital
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- $0.00 / 25KG
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2025-09-23
- CAS:744-80-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 2000
- Benzobarbital
-
- $15.00/ kg
-
2024-04-27
- CAS:744-80-9
- Min. Order: 1kg
- Purity: 99.912%
- Supply Ability: 10ton
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| | Benzobarbital Basic information |
| Product Name: | Benzobarbital | | Synonyms: | 1-benzoyl-5-ethyl-5-phenyl-2,4,6-trioxohexahydropyrimidine;1-benzoyl-5-ethyl-5-phenyl-barbituricaci;1-benzoyl-5-ethyl-5-phenylbarbituricacid;Benzobarbita;6(1h,3h,5h)-pyrimidinetrione,1-benzoyl-5-ethyl-5-phenyl-4;benzonal;benzoylluminal;benzoylphenobarbital | | CAS: | 744-80-9 | | MF: | C19H16N2O4 | | MW: | 336.34 | | EINECS: | 1592732-453-0 | | Product Categories: | Pharmaceutical Intermediates;API intermediates | | Mol File: | 744-80-9.mol |  |
| | Benzobarbital Chemical Properties |
| Melting point | 134.5°C | | Boiling point | 472.83°C (rough estimate) | | density | 1.3097 (rough estimate) | | refractive index | 1.5700 (estimate) | | form | Solid | | pka | 6.41±0.10(Predicted) |
| RIDADR | 3249 | | HazardClass | 6.1(b) | | PackingGroup | III | | Toxicity | dlt-mus-orl 20 mg/kg CYGEDX 10(2),1,76 |
| | Benzobarbital Usage And Synthesis |
| Chemical Properties | [Appearance] White crystalline powder with bitter taste [Solubility] Almost insoluble in water, slightly soluble in 95% ethanol, soluble in ether, soluble in chloroform [Melting point] 134-137℃ [Clarity and color of solution] 5ml1% 1N NaOH solution should be clarified and colorless [Acidity] 6.0-6.8 [Relevant impurities] Phenobarbital ≤0.8% [Diphenyl derivatives] ≤0.4% (TLC) Chloride] ≤0.005% [Sulfate] ≤0.025% [Sulfate ash] ≤0.1% [Heavy metal] ≤0.001% [Content] ≥99.0% | | Uses | is used in preparation method and composition for treating epilepsy including administering a Cholecystokinin-2 receptor antagonist and combination with antiepileptic agents. | | Safety Profile | Moderately toxic by ingestion.Experimental reproductive effects. Mutation datareported. When heated to decomposition it emits toxicfumes of NOx. | | Synthesis | Phenobarbital was synthesized using silver salt of phenobarbital and benzoyl chloride in catalyst-free reaction with about 20% yield. Benzoylphenobarbital was synthesized from phenobarbital and benzoyl chloride using 4 dimethylaminopyridine (abbreviated as DM AP) as a catalyst and triethylamine as an acid-fixing agent in 64% yield, w (benzoylphenobarbital) = 99%. |
| | Benzobarbital Preparation Products And Raw materials |
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