N4-Benzoyl-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-2',2'-diflurocytidine
| 中文名称 | N4-Benzoyl-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-2',2'-diflurocytidine |
|---|---|
| 中文同义词 | N-(1-((2R,4R,5R)-5-((双(4-甲氧基苯基)(苯基)甲氧基)甲基)-3,3-二氟-4-羟基四氢呋喃-2-基)-2-氧代-1,2-二氢嘧啶-4-基)苯甲酰胺;化合物 N4-BENZOYL-2'-DEOXY-5'-O-(4,4'-DIMETHOXYTRITYL)-2',2'- DIFLUROCYTIDINE |
| 英文名称 | N4-Benzoyl-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-2',2'-diflurocytidine |
| 英文同义词 | N4-Benzoyl-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-2',2'-diflurocytidine;Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2',2'-difluoro-;N4-Benzoyl-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-2',2'-difluorocytidine;N4-Benzoyl-2’-deoxy-5’-O-(4,4’-dimethoxytrityl)-2’,2’-diflurocytidine;N-(1-((2R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,3-difluoro-4-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide;N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine;(2R,3R,4R,5R)-5-(4-acetamido-3-methyl-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite |
| CAS号 | 142808-43-3 |
| 分子式 | C37H33F2N3O7 |
| 分子量 | 669.68 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 142808-43-3.mol |
| 结构式 |  |
N4-Benzoyl-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-2',2'-diflurocytidine 性质
| 密度 | 1.31±0.1 g/cm3(Predicted) |
|---|---|
| 酸度系数(pKa) | 8.39±0.20(Predicted) |
N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine 是一种嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制 DNA 合成，诱导细胞凋亡 (apoptosis) 等。