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| | ANTI-CLAUDIN-5 Basic information |
| Product Name: | ANTI-CLAUDIN-5 | | Synonyms: | Anti-Claudin 5, C-Terminal antibody produced in rabbit;ANTI-CLAUDIN-5;Transmembrane protein deleted in VCFS;CLD5;CLDN5;TMDVCF | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-CLAUDIN-5 Structure]() |
| | ANTI-CLAUDIN-5 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution | | biological source | rabbit |
| Storage Class | 10 - Combustible liquids |
| | ANTI-CLAUDIN-5 Usage And Synthesis |
| Uses | Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper) | | General Description | The CLDN5 (claudins) gene is mapped to human chromosome 22q11.21 and codes for a transmembrane protein, which is a component of tight junction. The protein is a part of blood-brain barrier. The encoded protein is 303 - 218 amino acids long. | | Biochem/physiol Actions | The CLDN5 (claudins) gene encodes a component of tight junction and serves as a selective barrier for solutes and water. Upregulation of CLDN5 was observed in migraine. The expression of CLDN5 is reduced in lung squamous carcinoma. CLDN5 is known to increase p21 and decrease cyclin D1, leading to the retardation of cell cycle G1 to S transition. Cldn5 maintains homeostasis of the central nervous system, being a part of blood-brain barrier. |
| | ANTI-CLAUDIN-5 Preparation Products And Raw materials |
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