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| | Fosamprenavir-d4 Basic information |
| | Fosamprenavir-d4 Chemical Properties |
| | Fosamprenavir-d4 Usage And Synthesis |
| Uses | Fosamprenavir-d4 is deuterium labeled Fosamprenavir. Fosamprenavir (Amprenavir phosphate;GW 433908) is a phosphate ester proagent of the antiretroviral protease inhibitor Amprenavir, with improved solubility[1]. Anti-HIV infection[1]. | | References | [1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Falcoz C, et al. Pharmacokinetics of GW433908, a prodrug of amprenavir, in healthy male volunteers. J Clin Pharmacol. 2002 Aug;42(8):887-98. DOI:10.1177/009127002401102803 |
| | Fosamprenavir-d4 Preparation Products And Raw materials |
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