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BOC Sciences
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| Products Intro: |
Product Name:2-Propylpiperidine hydrochloride CAS:15991-59-0 Purity:>=95% Remarks:Reach out to us for more information about custom solutions.
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| | (+/-)-2-PROPYLPIPERIDINE HYDROCHLORIDE* Basic information |
| Product Name: | (+/-)-2-PROPYLPIPERIDINE HYDROCHLORIDE* | | Synonyms: | (+/-)-2-PROPYLPIPERIDINE HYDROCHLORIDE*;Piperidine, 2-propyl-, hydrochloride (1:1);Coniine hydrochloride in methanol;Coniine hydrochloride-RM;Coniine hydrochloride, 10 mM in DMSO;(±)-Coniine (hydrochloride) | | CAS: | 15991-59-0 | | MF: | C8H18ClN | | MW: | 163.68822 | | EINECS: | | | Product Categories: | | | Mol File: | 15991-59-0.mol |  |
| | (+/-)-2-PROPYLPIPERIDINE HYDROCHLORIDE* Chemical Properties |
| Melting point | ~210 °C(lit.) | | storage temp. | Inert atmosphere,Room Temperature | | form | Solid | | color | White to off-white |
| Hazard Codes | Xi | | Risk Statements | 36 | | Safety Statements | 26 | | WGK Germany | - |
| | (+/-)-2-PROPYLPIPERIDINE HYDROCHLORIDE* Usage And Synthesis |
| Uses | (±)-Coniine hydrochloride (2-Propylpiperidine hydrochloride) is a potent nAChR agonist with an EC50 value of 0.3 mM. (±)-Coniine hydrochloride shows acute toxicity with an LD50 value of 7.7 mg/kg[1]. | | in vivo | (±)-Coniine hydrochloride (compound 1) (0.05 mg-0.2 mg; i.v.) shows acute toxicity with an LD50 value of 7.7 mg/kg[1]. | Animal Model: | 15-20 g, Swiss-Webster male mice[1] | | Dosage: | 0.05 mg-0.2 mg | | Administration: | I.v. | | Result: | Clinical signs was almost immediate after injection, beginning with piloerection, tail
flicking, and rapidly progressing to intention tremors, clonic convulsions, muscular weakness, lateral recumbency, and death; shows acute toxicity with an LD50 value of 7.7 mg/kg. |
| | References | [1] Lee ST, et al. Stereoselective potencies and relative toxicities of coniine enantiomers. Chem Res Toxicol. 2008 Oct;21(10):2061-4. DOI:10.1021/tx800229w |
| | (+/-)-2-PROPYLPIPERIDINE HYDROCHLORIDE* Preparation Products And Raw materials |
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