醋酸氯己定
| 中文名称 | 醋酸氯己定 |
|---|---|
| 中文同义词 | 氯已定二醋酸酯;醋酸氯己定;醋酸洗必泰,醋酸氯已定;醋酸氯己定对照品;湖北醋酸洗必泰原料药;醋酸洗必泰原料药生产厂家;1,6-双(N1-对氯苯基-N5-双胍基)己烷二醋酸盐;醋酸氯己定水合物 |
| 英文名称 | Chlorhexidine diacetate |
| 英文同义词 | Chlorhexidine (acetate hydrate);2-[N'-[6-[[Amino-[[amino-[(4-chlorophenyl)amino]methylidene]amino]methylidene]amino]hexyl]carbamimidoyl]-1-(4-chlorophenyl)guanidine diacetate;Chlorhexidine diacetate;CHLORHEXIDINE DIACETATE HYDRATE, 98;2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(4-chlorophenyl)-3,12-diimino-, acetate, hydrate (1:2:);Chlorhexidine acetate hydrate(1:2:x);TIANFU CHEM--Chlorhexidine diacetate;2,4,11,13-Tetraazatetradecanediimidamide,N,N''-bis(4-chlorophenyl)-3,12-diimino-,diacetate,hydrate |
| CAS号 | 206986-79-0 |
| 分子式 | C22H30Cl2N10.2C2H4O2.xH2O |
| 分子量 | 625.55 |
| EINECS号 | 205-516-1 |
| 相关类别 | 原料;广谱抑菌、杀菌;原料药;中间体;消毒防腐原料药;化合物：原料药;消毒防腐类原料;醋酸氯已定;化工;咔唑;医药化工类;皮肤外用原料;非抗生素类杀菌;医药原料;消毒类;化工原料 |
| Mol文件 | 206986-79-0.mol |
| 结构式 |  |
醋酸氯己定 性质
| 熔点 | 153-157°C |
|---|---|
| 储存条件 | room temp |
| 溶解度 | DMF：15 mg/ml；二甲基亚砜：15 mg/ml； DMSO:PBS(pH 7.2)(1:2)：0.33 mg/mL；乙醇：10 mg/ml |
| 形态 | 粉末 |
| 颜色 | 白色到近乎白色 |
| InChIKey | STXIUCWIIZWUGG-UHFFFAOYSA-N |
| SMILES | N(C1C=CC(Cl)=CC=1)C(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1C=CC(Cl)=CC=1.C(=O)(O)C |
Chlorhexidine acetate hydrate 是一种抗菌剂和防腐剂。Chlorhexidine acetate hydrate 可用于外伤后、手术前或注射前清洁皮肤。
Chlorhexidine acetate hydrate 是一种抗菌剂和防腐剂。Chlorhexidine acetate hydrate 可用于外伤后、手术前或注射前清洁皮肤。
| Animal Model: | One hundred and eighty male Imprinting Control Region (ICR) mice at 6 to8-wk-old (body weight, 25 ± 3 g) were randomized to six groups. |
| Dosage: | Chlorhexidine gluconate 0.05%, and Chlorhexidine gluconate 0.025%. |
| Administration: | One-time intraperitoneal injection. |
| Result: | A total of 48 mice (26.7%) developed postoperative intra-abdominal abscesses. Mice that had Chlorhexidine gluconate 0.05% lavage had significantly lower incidence of postoperative intra-abdominal abscesses compared with that of group D mice that had saline lavage only (P = 0.0113). Microscopic peritoneal fibrosis occurred significantly more among group E mice that had Chlorhexidine gluconate 0.05% lavage compared with group D mice that had saline lavage only (P = < 0.005). |
安全信息
| 危险品运输编号 | UN 3077 9 / PGIII |
|---|---|
| WGK Germany | 3 |
| RTECS号 | DU1930000 |
| 海关编码 | 29280090 |
| 存储类别 | 11 - 可燃固体 |
| 危险性类别 | 急性毒性 类别4 经口 危害水生环境-急性危害 类别1 危害水生环境-长期危害 类别1 眼部刺激 类别2 经皮刺激 类别2 特异性靶器官毒性-一次接触类别2 |
醋酸氯己定 化学药品说明书
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026/03/03 | 21498 | 氯已定二醋酸酯 Chlorhexidine diacetate hydrate, 98%, Thermo Scientific Chemicals | 206986-79-0 | 25g | 2679元 |
| 2025/05/22 | 21498 | 氯已定二醋酸酯 Chlorhexidine diacetate hydrate, 98%, Thermo Scientific Chemicals | 206986-79-0 | 5g | 790元 |
上游原料