SPLA2 INHIBITOR manufacturers
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| | SPLA2 INHIBITOR Basic information |
| Product Name: | SPLA2 INHIBITOR | | Synonyms: | S-3319;KH064;KWLUIYFCMHKLKY-NDEPHWFRSA-N;Benzenepentanoic acid, γ-[(1-oxo-7-phenylheptyl)amino]-4-(phenylmethoxy)-, (γS)-;5-BPP acid;sPLA2 inhibitor 1;sPLA2 inhibitor 1,sPLA-2 inhibitor 1;(S)-5-(4-(Benzyloxy)phenyl)-4-(7-phenylheptanamido)pentanoic acid | | CAS: | 393569-31-8 | | MF: | C31H37NO4 | | MW: | 487.63 | | EINECS: | | | Product Categories: | | | Mol File: | 393569-31-8.mol |  |
| | SPLA2 INHIBITOR Chemical Properties |
| Melting point | 133-135 °C | | Boiling point | 720.9±60.0 °C(Predicted) | | density | 1.124±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: >5 mg/mL, freely soluble | | form | solid | | pka | 4.57±0.10(Predicted) | | color | white |
| | SPLA2 INHIBITOR Usage And Synthesis |
| Uses | sPLA2 inhibitor protects against intestinal reperfusion injury which was evident through biological studies in rats. | | in vivo | KH064 (compound 2b; oral; 5 mg/kg/day; on Days 10-13 after inoculation with arthritogen) shows substantial inhibition of the oedema. Drug-treated rats shows mild capsular oedema and minimal infiltration of macrophages into the red pulp[1]. | | IC 50 | sPLA2: 29 nM (IC50) |
| | SPLA2 INHIBITOR Preparation Products And Raw materials |
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