| Company Name: |
T&W GROUP |
| Tel: |
021-61551611 13296011611 |
| Email: |
contact@trustwe.com |
VK-28 manufacturers
- VK-28
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- $79.00
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2026-08-30
- CAS:312611-92-0
- Purity: 99.87%
- Supply Ability: 10g
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| Product Name: | VK-28 | | Synonyms: | 5-[[4-(2-hydroxyethyl)piperazin-1-yl]methyl]quinolin-8-ol;8-Quinolinol, 5-[[4-(2-hydroxyethyl)-1-piperazinyl]methyl]-;VK28,VK 28;VK-28, 10 mM in DMSO | | CAS: | 312611-92-0 | | MF: | C16H21N3O2 | | MW: | 287.36 | | EINECS: | | | Product Categories: | | | Mol File: | 312611-92-0.mol |  |
| | VK-28 Chemical Properties |
| Melting point | >230℃ | | storage temp. | 2-8°C | | solubility | H2O: insoluble | | form | solid | | color | off-white |
| Hazard Codes | Xi | | Risk Statements | 41 | | Safety Statements | 26-39 | | WGK Germany | 3 |
| | VK-28 Usage And Synthesis |
| Uses | VK-28, a brain-permeable iron chelator, inhibits both basal and Fe/ascorbate-induced mitochondrial membrane lipid peroxidation, with an IC50 of 12.7 μM. VK-28 exhibits significant neuroprotective effects on ICV-6-OHDA. VK-28 can be used for the research of Parkinson’s disease and other neurodegenerative diseases[1]. | | References | [1] Shachar DB, et al. Neuroprotection by a novel brain permeable iron chelator, VK-28, against 6-hydroxydopamine lession in rats. Neuropharmacology. 2004 Feb;46(2):254-63. DOI:10.1016/j.neuropharm.2003.09.005 |
| | VK-28 Preparation Products And Raw materials |
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