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| | 2,2',4,4'-TETRABROMODIPHENYL ETHER Basic information |
| Product Name: | 2,2',4,4'-TETRABROMODIPHENYL ETHER | | Synonyms: | BDE No 47;2,2',4,4'-TETRABROMODIPHENYL ETHER;PBDECONGENER47;BDE-47;2,2μ,4,4μ-TetraBDE, 2,2μ,4,4μ-Tetrabromodiphenyl ether solution, PBDE 47;BDE No 47 solution;2,2’,4,4'Tetrabromodiphenyl ether,50ug/ml in Isooctane;1,1'-Oxybis(2,4-dibromobenzene) | | CAS: | 5436-43-1 | | MF: | C12H6Br4O | | MW: | 485.79 | | EINECS: | 208-759-1 | | Product Categories: | | | Mol File: | 5436-43-1.mol |  |
| | 2,2',4,4'-TETRABROMODIPHENYL ETHER Chemical Properties |
| Melting point | 83-84℃ (ethanol ) | | Boiling point | 396 °C | | density | 2.161±0.06 g/cm3(Predicted) | | Fp | -12 °C | | storage temp. | Sealed in dry,Room Temperature | | solubility | Methanol: Soluble | | form | Solid | | color | White to off-white | | Henry's Law Constant | 9.1×10-1 mol/(m3Pa) at 25℃, Long et al. (2017) | | Major Application | environmental | | InChI | InChI=1S/C12H6Br4O/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6H | | InChIKey | XYBSIYMGXVUVGY-UHFFFAOYSA-N | | SMILES | C1(OC2=CC=C(Br)C=C2Br)=CC=C(Br)C=C1Br | | EPA Substance Registry System | Benzene, 2,4-dibromo-1-(2,4-dibromophenoxy)- (5436-43-1) |
| Hazard Codes | F,Xn,N | | Risk Statements | 11-38-50/53-65-67 | | Safety Statements | 60-61-62-33-29-16-9 | | RIDADR | UN 1262 3/PG 2 | | WGK Germany | 2 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Aquatic Acute 1
Aquatic Chronic 1
Asp. Tox. 1
Flam. Liq. 2
Skin Irrit. 2
STOT SE 3 |
| | 2,2',4,4'-TETRABROMODIPHENYL ETHER Usage And Synthesis |
| Uses | 2,4,2'',4''-Tetrabromodiphenyl Ether, is one of the Polybrominated di-Ph ethers (PBDEs), which are a new class of global, persistent, and toxic contaminants. It is used as Brominated flame retardants (BFRs) in various consumer products. One of the new POPs under the Stockholm Convention | | Definition | ChEBI: 2,2',4,4'-Tetrabromodiphenyl ether is an organobromine compound and an aromatic ether. | | Synthesis | The general procedure for the synthesis of 2,2,4,4-tetrabromodiphenyl ether using 2,4-dibromophenol as starting material: SiO2-ZrO2 (0.05 g) and 2,4-dibromophenol (2.50 g) were placed in a mortar and fully ground for 12 min. After the reaction was completed, n-pentane was used as eluent, and the reaction mixture was separated and purified by silica gel column chromatography, resulting in 2.16 g of white solid product in 89% yield. | | References | [1] Patent: CN106957218, 2017, A. Location in patent: Paragraph 0043-0047
[2] AHMED KHALIL. Developmental Exposure to 2,2',4,4'-Tetrabromodiphenyl Ether Permanently Alters Blood-Liver Balance of Lipids in Male Mice.[J]. Frontiers in Endocrinology, 2018: 548. DOI: 10.3389/fendo.2018.00548
[3] XIAOJUAN CHEN. BDE-47 disrupts axonal growth and motor behavior in developing zebrafish[J]. Aquatic Toxicology, 2012, 120: Pages 35-44. DOI: 10.1016/j.aquatox.2012.04.014
[4] CATHRINE THOMSEN*. Changes in Concentrations of Perfluorinated Compounds, Polybrominated Diphenyl Ethers, and Polychlorinated Biphenyls in Norwegian Breast-Milk during Twelve Months of Lactation[J]. Environmental Science and Technology, 2010, 44 24: 9550-9556. DOI: 10.1021/es1021922
[5] CHE-JUNG CHANG . Serum concentrations of polybrominated biphenyls (PBBs), polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) in the Michigan PBB Registry 40 years after the PBB contamination incident[J]. Environment International, 2020, 137: Article 105526. DOI: 10.1016/j.envint.2020.105526 |
| | 2,2',4,4'-TETRABROMODIPHENYL ETHER Preparation Products And Raw materials |
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